Tu - Adoptive therapy: (ex vivo) CTLs, TCR engineered T cells and CART cells. Flashcards

1
Q

What is the difference between hot tumors and cold tumors?

A

Hot tumors have lots of T cells, cold tumors don’t

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2
Q

What is a chimeric antigen receptor?

A

A chimera between an antibody and the T cell receptor.

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3
Q

What are 2 limitations of CART cells? (2)

A

CART cells don’t live long in patients, also tumors are able to make mutations so the CART cells are not able to recognise the tumor cells.

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