Trematodes Flashcards

(55 cards)

1
Q

Cholangiocarcinoma

A

Clonorchis sinensis

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2
Q

Typical small brownish operculated egg

A

Clonorchis sinensis

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3
Q

Chlonorchis Tx

A

Praziquantel

Albendazole

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4
Q

Chinese liver fluke

Ingestion of raw or undercooked fish

A

Chlonorchis sinensis

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5
Q

Undercooked fish with encysted larvae (metacercariae) -> duodenum -> immature flukes enter bile duct -> adults -> release eggs -> feces -> snails -> miracidia

A

Clonorchis sinensis

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6
Q

Clonorchis sinensis occupies or encysts the

A

2nd part of duodenum

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7
Q

Diagnostic stage of Clonorchis sinensis

A

Embryonated eggs passed in feces

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8
Q

Infective stage of Chlonorchis sinensis

A

Metacercariae in flesh of fish

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9
Q

Inflammation and obstruction of biliary tract

A

Chlonorchis sinensis

Also ascaris

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10
Q

Chlonorchis is seen on microscopy as

A

Old fashioned electric bulb

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11
Q

Oriental lung fluke

Raw or undercooked crab meat crustacean

A

Paragonimus westermani

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12
Q

Paragonimus westermani definitive host

A

Human

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13
Q

Paragonimus westermani 1st intermediate host

A

Snail

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14
Q

Paragonimus westermani intermediate host

A

Crab

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15
Q

Hemoptysis

Cough

A

Paragonimus westermani

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16
Q

Rash
Eggs in bladder
Inflammation of bladder

A

Schistosoma hematobium

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17
Q

Schistosomiasis is also known as

A

bilharzia
bilharziosis
snail fever

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18
Q

Schistosoma intermediate host

A

Oncomelia quadrasi

Snail

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19
Q

Dioecious (sexes are separate)

Male is larger than female

Blood trematode

A

Schistosoma

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20
Q

Schistosoma Dx

A

Eggs

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21
Q

Egg of schistosoma mansoni

A

large lateral spine

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22
Q

S japonicum egg

A

Small lateral spine

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23
Q

S haematobium egg

A

Terminal spine

24
Q

Urinary schistosomiasis

A

S haematobium

25
Schistosoma definitive host
Human
26
Infective stage of Schistosoma
Cercariae
27
Schistosoma diagnostic stage
Eggs in feces (mansoni, japonicum) | Eggs in urine (haematobium)
28
Schistosoma migrates and matures in the
liver into adults and then to bowel or rectum to lay eggs or bladder
29
Schistosoma mansoni and japonicum migrates to
Mesenteric venules | Pipestem Fibrosis
30
S haematobium migrates to
urinary venules
31
S mansoni prefers
colon
32
S japonicum prefers the
Small intestine
33
S haematobium is precursor for
urinary bladder cancer
34
Schistosoma Tx
Praziquantel | Oxamniquine
35
S japonicum Oriental blood fluke Snail host
Oncomelania hupensis/philippinensis
36
S mansoni Snail host
Biomphlaria glabrata
37
S intercalatum Snail host
Bulinus forskalii | Bulinus africanus
38
S haematobium Snail host
Bulinus truncatus
39
Schistosomiasis is endemic in
12 regions ``` Bohol Mindoro oriental Sorsogon Samar Leyte ``` ``` By region Surigso Agusan Samar Leyte ```
40
3 factors for disease process of Schistosoma
Presence of snail intermediate host Method of disposal of human excreta Contact with cercaria-infected water
41
Dermatitis (cercarial invasion)
Swimmer’s itch | Schistosoma
42
Parasites approach sexual maturity and commencement of oviposition of Schistosoma
Katayama fever | Acute schistosomiasis
43
Results for associated antigen excess | Chronic schistosomiasis
Granuloma formation in | Schistosoma
44
Schistosoma causes
Granuloma formation Organomegaly Obstruction (portal hypertension -> esophageal varices) Hydroureter & hydronephrosis
45
UTZ finding of Schistosomiasis
Lace like pattern
46
Phases of cercarial invasion
Cercarial invasion Intestinal phase Hepatosplenic phase
47
Form of dermatitis most commonly caused by S mansoni S japonicum 2-3 days after invasion
Swimmer’s itch
48
Occurs during worm. Maturation and oviposition (4-8 weeks after invasion) Serum-like sickness fever, LAD, hepatosplenomegaly High Eosinophilia Antibodies detected in seum before eggs are identified in excreta
Katayama fever
49
Few months after infection Colicky abdominal pain Bloody diarrhea Anemia Fatigue, inability to perform daily routine functions Growth retardation Severity = worm burden Runs chronic course -> colonic polyposis
Intestinal phase
50
Esophageal varices Caput medusae Superior rectal veins Liver function deterioration Ascites Hypoalbuminemia Coagulation defects
Hepatosplenic phase
51
Migratory worm deposit eggs in brain and induce granulomatous response Jacksonian epilepsy S japonicum Transverse myelitis
CNS Schistosomiasis | S japonicum
52
Stool exam for Schistosomiasis
Kato-katz thick smear | + for heme or grossly bloody
53
Schistosomiasis PCR
94. 4 sensitivity 99. 9 specificity Can detect DNA in stool or urine
54
Schistosoma serum test
Circum Oval Precipitin
55
Schistosomiasis Tx
Praziquantel