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Microbiology > Proteus and Pseudomonas > Flashcards

Proteus and Pseudomonas Flashcards

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1
Q

Motile
Swarming motility on BAP
Urease +
Causes UTI and staghorn renal calculi

A

Proteus mirabilis/vulagaris

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2
Q

Proteus struvite stones “coffin lid” appearance

A

Magnesium
Ammonium phosphate

MAP

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3
Q

Proteus mirabilis/vulagris Tx

A

Fluoroquinolone

TMP-SMZ

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4
Q

Enzyme that catalyzed hydrolysis of urea

Urea is split to form ammonia and CO2

A

Urease

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5
Q

Urease + organisms

Pink because of ammonia

A

Proteus
H pylori
Ureaplasma urealyticum

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6
Q

Favors formation of stagnorn calculi

A

Urease

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7
Q

Responsible for Swarming growth of Proteus

A

Peritrichous flagella

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8
Q

Green colored enzyme of Proteus because of presence of Phenylpyruvic acid

A

Phenylalanine deaminase + 10% FeCl3

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9
Q

Proteus antigen

that cross react with various strains of rickettsiae

A

OX-19 (vulgaris)
OX-2 vulgaris
OX-K (Proteus mirabilis)

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10
Q

Proteus motility

A

Swarming

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11
Q

Proteus flagella

A

Peritrichous

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12
Q

Proteus pathogenic factor

A

Urease

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13
Q

Proteus renal stone

A

Staghorn calculi MAP

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14
Q

Cross reacts with rickettsial antibodies

A

Proteus vulgaris OX strain

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15
Q

Non-fermenting, oxidase +
Fruity, grape-like
Pyocyanin +
Pyoverdin +

Burn/neutropenic/hospitalized/ventilated

A

Pseudomonas aeruginosa

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16
Q

Septicemia from Pseudomonas comes from

A

Exthyma gangrenosum

17
Q

Old name of pseudomonas

A

Bacillus pyocyanius

Pyocyanin (blue pus)

18
Q

Pseudomonas causes

A

Pyocyanin (blue pus)

Shanghai fever

19
Q

Colonizes respiratory tract of hospitalized patients

Can grow in simple aqueous solutions: respiratory therapy, anesthesia equipment, IV fluid and distilled water

A

Pseudomonas

20
Q 
Gram -
Oxidase +
Non fermenting
Obligate aerobe
Loves wet environment
A

Pseudomonas

21
Q

Pseudomonas pigments

A

Pyocyanin (blue-green)
Fluorescein (green-yellow, fluorescent)
Best produced by King’s pigment
Pyoverdin (yellow-green pigment that fluoresces under ultraviolet light in burn)

22
Q

Damages cilia and mucosal cell of respiratory tract

A

Pyocyanin

23
Q

Pseudomonas toxins

A

Toxin A - ADP ribosylation of EF 2; NADase similar to diptheria

24
Q

Slime layer is anti-phagocytic

Gun metal appearance of colonies

A

Pseudomonas

25
Q

Pseudomonas can cause

A

Skin and soft tissue - hot tub folliculits; burn; ecthyma gangrenosum*

Ear infection - diffuse otitis externa

Pneumonia - ICU, vent, cystic fibrosis*

26
Q

Fruity odor of pseudomonas is because of the presence

A

trimethylamine (aminoacetophenone)

27
Q

Most common cause of Gram - nosocomial pneumonia

A

Pseudomonas

28
Q

Pseudomonas Tx

A

Ceftazidime (monotherapy)

Cefepime

Pip/Taz or Imipenem
Amikacin

29
Q

What oral antibiotic has adequate antipseudomonal coverage?

A

Ciprofloxacin

Microbiology (16 decks)

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