Cestode Flashcards
Broad or fish tapeworm
D latum
Diphyllobothriasis
Largest human tapeworm
D latum
2 elongated sucking grooves
Bothria
No circular suckers or hooks
Gravid uterus forms rosettes
D latum
Eggs Oval, operculum at one end
D latum
Longest and largest of tapeworms
rosette appearance
Sucking groove of scolex
Oval eggs with lid-like opening (operculum)
D latum
D latum transmission
Ingestion of raw or undercooked fresh water fish
D latum definitive host
Where parasite reaches its maturity
Human
D latum intermediate host
Organism that supports immature, nonrepro form
Copepod 1st intermediate
Fish 2nd intermediate
Little damage in gut causing diarrhea and pain but may cause this type of anemia
Pernicious anemia
B12 def
D latum Dx
Eggs or proglottids
D latum Tx
Praziquantel
Increases permeability of worm membrane
Influx of calcium
Praziquantel
Ca influx from Praziquantel lead to
worm spasm and paralysis
D latum life cycle
Human passes egg to feces
Copepod ingests eggs
Fish ingests eggs
Human ingests eggs
D latum causes
Megaloblastic anemia
Pernicious anemia
Dog tapeworm
Hydatid worm
Echinococcus granulosus
Scolex: 4 suckers
Double circle of hooks
Adult worm only 3 proglottids
Echinococcus granulosus
extra-intestinal tapeworm infection
Unilocular hydatid cyst
Most important definitive host of echinococcus granulosus
Dog/sheep
Humans in e granulosis are only
dead-end/accidental host
E granulosus is usually found in
rural areas
grazing areas
Dog eats entrails (liver) of sheep -> hydatid cyst -> adult worm in gut -> eggs passed in feces -> sheep (and human)
E granulosis
Endemic in sheep raising areas
Ingest entrails of sheep
E granulosus
E granulosus affects lungs as
E multilocularis
E granulosus spleen cyst
E granulosus
Most common cause of splenic abscess
Echinococcus
Scolex is pyriform
E granulosus
Protoscoleces
Hydatid sand
Danger on rupture of hydatid cyst
Anaphylactic shock
E granulosus Gold Standard Dx
UTZ
E granulosus UTZ diagnostic feature
Water lily sign
Hydatid cyst occurs 60% in
Liver
Spleen
E granulosis Diagnostic intradermal test
Casoni skin test
E granulosus Tx
Most effective
Surgical removal
Extirpation
Drug for E granulosus
Albendazole
Mebendazole
Taeniasis and Cysticercosis
Pork tapeworm
Scolex: 4 suckers, circle of hooks
Gravid proglottid
Taenia solium
Scolex of t solium
Cephalic rostellar hooklets
Mature segments of t solium
Broader than long
Pork tapeworm
Rostellar hooks
Broader than long
Taenia solium
Ovum is spherical thick wall that that has STRIATIONS
Taenia solium
Adult worm t solium
Taeniasis
Larvae form of t solium
Cysticercosis
If egg of t solium reaches brain
Neurocysticercosis
Most common brain infection worldwide
Neurocysticercosis
Undercooked pork infected with cysticerci -> humans larvae attach gut -> adult worm with proglottid -> pass in feces -> pigs
May infect brain
T solium
Muscle parasites
Trichinella spiralis
T solium
Lab diagnosis of t solium
CT scan
Biopsy of infected tissue reveal calcified cysticerci
Calcifications in brain
Toxoplasmosis
MTB
Schistosomiasis
Neurocystercosis
T solium Tx
Praziquantel for intestinal worms and cerebral cysticercosis (drug of choice)
Surgical excision
Albendazole
Intestinal worm t solium Tx
Niclosamide
Neurocystercosis trigerring inflammation -> seizure
Jacksonian march - focal seizure
Superior tx for T solium
Better penetration of CSF
Give with
Albendazole
Dexamethasone
Better than praziquantel
Beef tapeworm
Taeniasis
Scolex: 4 suckers, no hooks
Absent cephalic hooklet
Gravid proglottid: 15-20
Taenia saginata
Humans infected by eating raw or undercooked beef containing larvae (cysticerci)
Migrates to skeletal muscle
Taenia saginata
T saginta intermediate host
Cattle
T saginatum Definitive host
Human
Cysticercosis does not occur
T saginata
T saginata treatment
Praziquantel
Small fox tapeworm
Alveolar echinococcosis
Echinococcus multilocularis
Dwarf tapeworm
Entire worm - small 40 mm long
No intermediate host
Person to person most often asymptomatic
Heavy infection weakness, headaches, anorexia, abdominal pain and diarrhea
Tx Praziquantel
Hymenolepsis nana