Tissue Nematodes Filaria Flashcards
Convoluted filaria producing Black River Blindness (2nd most common cause of blindness after chlamydia trachomatis)
Hyper and hypopigmented spots with dermatitis
Humans only definitive host
No animal reservoir
Endemic in rivers of tropical Africa and Central America
Onchocerca volvulus
Onchocerca infective stage
Larvae
Onchocerca intermediate host
Blackfly
Onchocerca diagnostic stage
Eosinophilia
Microfilariae skin biopsy
Found in skin, lymphatics
Microfilariae in eye cause blindness
Inflammatory nodules in skin
Onchocerca volvulus
Onchocerca tx microfilariae
Ivermectin
Onchocerca for eye infection
Suramin
Sclerosing keratitis
Leopard skin
Onchocerca volvulus
Firm, movable, non-tender onchocercal nodule
Onchocerca volvulus
Skin reaction that occurs in humans when microfilariae of Onchocerca volvulus in cutaneous site are killed by administration of diethylcarbamazine
Mazzoti reaction
Filariasis
Pointed tail free of nuclei
Human infected when female mosquito
Anopheles and culex deposi larvae on skin and infect lymphatics
Causes elephantiasis
Wuchereria bancrofti
Adult worms cause inflammation that blocks lymphatic vessels -> edema -> elephantiasis
Lymphadenopathy
Cough from microfilariae in lungs
Eosinophilia
Wuchereria
Wuchereria Dx
Thick blood smear (taken at night)
Demonstrate microfilariae
Wuchereria tx
Diethylcarbamazine
Filariasis bancrofti Female anopheles, culex Humans only definitive host Microfilariae Blocks lymphatic vessels (elephantiasis)
Tail free of nuclei
Wuchereria bancrofti