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Microbiology > Parasitology > Flashcards

Parasitology Flashcards

1
Q

4 groups of protozoa

A

Sarcodina (amebas)
Sporozoans
Mastigophora (flagellates)
Ciliates

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2
Q

Metazoa 2 Phyla

A

Nemathelminthes (Round worms)

Platyhelminthes (Flat worms)

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3
Q

Platyhelminthes

A

Trematoda

Cestoda

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4
Q

Amoeba

A

E histolytica
E coli
Endolimax nana
Iodamoeba buetschlii

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5
Q

Amebic dysentery
Liver abscess

Motile amoeba
Forms cysts with 4 nuclei
E coli = 8 nuclei

A

E histolytica

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6
Q

Cyst -> humans -> trophozoites in small intestines ->colon -> cysts -> stool

A

E hystolitica

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7
Q

E histolytica transmission

A

Fecal oral

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8
Q

E histolytica trophozoites invade

A

colon (submucosa teardrop or flask shaped ulcers) -> bloody stools

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9
Q

Reaches portal blood circulation -> liver abscess R lobe -> spreads through diaphragm to lungs

Amebic abscess of the brain

A

E histolytica

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10
Q

E histolytica loves this part of liver

A

R posteroinferior lobe

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11
Q

E histolytica dx

A

Trophozoites
Cysts in stool *
Indirect hemagluttination

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12
Q

E histolytica

Tx

A

Metronidazole

Iodoquinol

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13
Q

Amoeba life cycle

A 
Non invasive colonization 
R side of colon (Amoebic colitis)
Extraintestinal liver (Amoebic liver abscess)
Brain 
Stool exam cyst
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14
Q

Infective stage of E histolytica

A

Cyst mature 4 nuclei

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15
Q

Amoebic liver abscess

A

Anchovy paste

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16
Q

Ingested RBC
Bull’s eye karyosome

Cigar shaped chromatoidal body

A

E hystolitica

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17
Q

Whisk broom

Chromatoidal body

A

Entamoeba coli

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18
Q

Comma shaped

Chromatoidal body

A

Endolimax nana

19
Q

Glycogen vacuole

A

Iodamoeba buetschlii

20
Q

Ring dot nuclei

A

Entamoeba hystolitica

21
Q

Peripheral chromatin

Central karyosome

A

Entmoeba hystolitica

22
Q

Luminal and extraluminal amecides

23
Q

The right lobe is 4 times more likely to be involved than the left because

A

it receives bulk of the venous drainage from the colon

24
Q

Anchovy paste is brought about by

A

Amoebic protease liquefying liver

25
Q

Dreaded complication of amoebiasis with rupture of hepatic abscess reaching the thoracic cavity

A

Amoebic pericarditis

26
Q

Luminal amebicide

A

Iodoquinol
Paromomycin
Diloxanite Furoate

DIP

27
Q

Tissue amebicide

A

Nitroimidazole
Metronidazole
Tinidazole

28
Q

Free living amoeba

A

Naegleria fowleri

Acanthamoeba

29
Q

Dormant form of Naegleria

30
Q

Feeding and replicating form

A

Trophozoite

31
Q

Naegleria
Acanthamoeba

mode of transmission

A

swimming in contaminated rivers, pools
inhalation
diving in warm, still waters

32
Q

Naegleria gains access to the brain through the

A

Cribriform plate of ethmoid multiplying along base of the brain
Frontal lobe

33
Q

Primary amoebic Meningooencephalitis with death in one week

A

Naegleria meningitis

34
Q

Inhabits fresh brackish and salt water, moist soil and decaying vegetation

A

Naeglaria fowleri

35
Q

Primary Amebic Encephalitis incubation period

36
Q

Headache, fever, lethargy, rhinitis, nausea, vomiting and disorientation

Photophobia, CN III, CN IV and or CN VI
Coma and death within a week

A

Primary Amoebic Encephalitis

37
Q

Primary Amoebic Encephalitis tx

A

Amphotericin B

38
Q

Investigational breast cancer and anti leishmania drug

Shown amoeba-killing activity against free living amoebae, including Naegleria fowleri

A

Miltefosine

39
Q

Skin lesions, uveitis and corneal ulceration, contamnated lens solutions

A

Acanthamoeba

40
Q

Acanthamoeba is notoriously associated with infection of

A

contact lens

41
Q

Usually in immunocompromised

Severe headache, nausea following swim; ulcerative eye infection

A

Granulomatous Amebic Encephalitis

42
Q

Acanthamoeba Tx

A 
Amphotericin B
Miconazole
Rifampin
Propamidine
Neomycin
43
Q

Acanthamoeba Dx

A

Presence of organisms in CSF

Corneal scrapings

Microbiology (16 decks)

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