transplant 1

Question 1

define autograft

Answer 1

A transplant of tissue from one to oneself

Question 2

define isograft

Answer 2

organs or tissues are transplanted from a donor to a genetically identical recipient (identical twins)

Question 3

define xenograft

Answer 3

A transplant of organs or tissue from one species to another

Question 4

define allograft

Answer 4

transplanted organ or tissue from a genetically non-identical member of the same species

Question 5

What is the federal regulatory body that ensures the success and efficiency of the U.S. transplantation system

Answer 5

Organ Procurement and Transplantation Network (OPTN)

Question 6

OPTN develops polices governing what specific things?

Answer 6

1. Organ recovery, matching, distribution and transportation
2. Collecting and managing scientific data about organ donation and transplantation
3. National organ waiting list database

Question 7

What is the non-profit, scientific and educational organization that carries out OPTN regulations concerning organ transplant

Answer 7

United Network for Organ Sharing (UNOS)

Question 8

what are some of the responsibilities of UNOS

Answer 8

1. collect data about every transplant event occurring in the United States
2. facilitate the organ matching and placement process
3. bring together medical professionals, transplant recipients and donor families to develop organ transplantation policy

Question 9

what are types of organs that patients are able to receive transplants for

Answer 9

1. kidney
2. liver
3. pancreas
4. heart
5. small bowel
6. lung

Question 10

what types of organs are translpantend from living donors

Answer 10

1. kidney
2. liver
3. pancreas
4. small bowel (rare)

Question 11

what are the indications for a kidney transplant

Answer 11

1. Diabetic nephropathy
2. Hypertension
3. Glomerulonephritis
4. Polycystic kidney disease

Question 12

what are the indications for a liver transplant

Answer 12

1. Alcoholic liver disease
2. Hepatitis B & C (in the U.S.)
3. Hepatic tumors
4. Metabolic disorders
5. Cryptogenic cirrhosis
6. Polycystic liver disease

Question 13

what are the indications for a pancreas transplant

Answer 13

1. diabetes

2. pancreatic tumor

Question 14

what are the indications for a heart transplant

Answer 14

1. Cardiomyopathy
2. Coronary artery disease
3. Congenital disease

Question 15

what are the indications for a small bowel transplant

Answer 15

small bowel syndrome

Question 16

what are the indications for a lung transplant

Answer 16

1. Cystic fibrosis
2. Idiopathic pulmonary fibrosis
3. Primary pulmonary hypertension
4. COPD/emphysema

Question 17

what are the absolute contraindications to organ donation

Answer 17

1. Chronic renal disease (kidney only?)
2. Age > 70
3. Potentially metastasizing malignancy
4. Severe hypertension
5. Untreated bacterial sepsis
6. Current IV drug abuse
7. Hepatitis B surface antigen positive•HIV positive
8. Prolonged warm ischemia (down time)

Question 18

What are the general recipient contraindications for transplants

Answer 18

1. Obesity (BMI > 35)
2. Uncontrolled infection
3. Malignancy (must be cancer free for two years)
4. Continued substance abuse
5. Poor family/social support
6. Uncontrolled psychiatric disorder
7. Medical noncompliance