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THERAPEUTICS III TEST 4 > Prostate 2 > Flashcards

Prostate 2 Flashcards

1
Q

what is abiraterone’s MOA

A

inhibits testosterone synthesis

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2
Q

what is a pure androgen receptor antagonist

A

enzalutamide

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3
Q

what is specifically inhibited by abiraterone

A

CYP17

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4
Q

what are some of the problems involved with mineralocorticoid excess (MCE)

A

hypokalemia
HTN
fluid retention

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5
Q

how can mineralocorticoid excess (MCE) be abided

A

Prednisone BID prevent tgis

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6
Q

what are the adverse effects of abiraterone

A 
mineralocorticoid excess (MCE)
adrenocortical insufficiency (ADI)
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7
Q

what are options for treating bone metastases

A

bisphosphonates (zoledronic acid or pamidronate)

denosumab

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THERAPEUTICS III TEST 4 (18 decks)

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