hematologic malignancies 3 Flashcards
what form of leukemia is most common with the elderly
chronic lymphocytic anemia
what is the malignant cell in chromic lymphocytic anemia
B lymphocyte
what drug is an anti CD20 monoclonal antibody
rituximab
what type of cancer can be induced through an infection, or autoimmune disease
non-Hodgkin lymphoma
what is used in treatment of almost all non-Hodgkin lymphomas
rituximab
what drug is an antibody linked to a radioactive isotope of Yttrium 90
ibritumomab
what is the standard chemo regimen for non-hodgkins lymphoma
R-CHOP rituximab Cyclophosphamide Doxorubicin Vincristine Prednisone
What is a usually indolent form of non-Hodgkins lymphoma is caused by H. Pylori
Mucosa associated lymphoid tissue (MALT)
what is the only type of non-Hodgkins Lymphoma that bortezomib (Velcade) works for
Mantle Cell Lymphoma
If a patient asks you to counsel them about Non-Hodgkins Lymphoma what is an appropriate response
NHL is an array of different kinds of cancers. It is hard to give a prognosis without more information
what is a malignancy of Reed-Sternberg cells with no clear cause
Hodgkin’s Lymphoma
what is a malignancy of Reed-Sternberg cells with no clear cause
Hodgkin’s Lymphoma
what are the signs and symptoms of hodgkins lymphoma
- painless, rubbery, enlarged lymph nodes
- fatigue
- malaise
- pruritis
- B symptoms (fever, night sweats, weight loss)
what is the classic chemotherapy for hodgkins lymphoma
doxorubicin, bleomycin, vincristine, and dacarbazine
what are some long term complications with chemotherapy
- most patients become sterole
2. threefold increase risk of another cancer
