Toxicities and antidotes Flashcards

1
Q

Acetaminophen

A

N-acetylcysteine (replenishes glutathione

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2
Q

AChE inhibitors, organophosphates

A

Atropine followed by pralidoxime

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3
Q

Amphetamines (basic)

A

NH4Cl (acidify urine)

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4
Q

Antimuscarinic, anticholinergic agents

A

physostigmine salicylat (control hyperthermia)

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5
Q

Benzodiazepines

A

flumazenil

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6
Q

beta blockers

A

glucagon

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7
Q

CO

A

100% O2, hyperbaric O2

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8
Q

Copper, arsenic, gold

A

penicillamine

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9
Q

Cyanide

A

Nitrite + thiosulfate, hydroxocobalamin

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10
Q

Digitalis

A

Anti-dig fab fragments

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11
Q

heparin

A

protamine sulfate

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12
Q

iron

A

deFeroxamine, deFErasirox

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13
Q

lead

A

EDTA, dimercaprol, succimer, penicillamine

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14
Q

mercury, arsenic, gold,

A

diMERCcaprol, succimer

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15
Q

Methanol, ethylene glycol (antifreeze)

A

Fomepizole > ethanol, dialysis

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16
Q

METHemoglobin

A

METHylene blue, vit C

17
Q

opioids

A

naloxone

18
Q

salicylates

A

NaHCO3 (alkalinzie urine, dialysis)

19
Q

TCAs

A

NaHCO3 (plasma alkalinization)

20
Q

tPA, streptokinase, urokinase

A

Aminocarpoic acid

21
Q

Warfarin

A

Vit K, plasma (if active bleeding)