Toxicities and antidotes Flashcards
Acetaminophen
N-acetylcysteine (replenishes glutathione
AChE inhibitors, organophosphates
Atropine followed by pralidoxime
Amphetamines (basic)
NH4Cl (acidify urine)
Antimuscarinic, anticholinergic agents
physostigmine salicylat (control hyperthermia)
Benzodiazepines
flumazenil
beta blockers
glucagon
CO
100% O2, hyperbaric O2
Copper, arsenic, gold
penicillamine
Cyanide
Nitrite + thiosulfate, hydroxocobalamin
Digitalis
Anti-dig fab fragments
heparin
protamine sulfate
iron
deFeroxamine, deFErasirox
lead
EDTA, dimercaprol, succimer, penicillamine
mercury, arsenic, gold,
diMERCcaprol, succimer
Methanol, ethylene glycol (antifreeze)
Fomepizole > ethanol, dialysis
METHemoglobin
METHylene blue, vit C
opioids
naloxone
salicylates
NaHCO3 (alkalinzie urine, dialysis)
TCAs
NaHCO3 (plasma alkalinization)
tPA, streptokinase, urokinase
Aminocarpoic acid
Warfarin
Vit K, plasma (if active bleeding)