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drug reactions Flashcards

1
Q

Cardio - what drugs cause flushing?

A

Vancomycin, Adenosine, Niacin, Ca channel blockers

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2
Q

Cardio - coronary vasospasm

A

Cocaine, sumatriptan, ergot alkaloids

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3
Q

Cardio - Torsades

A

Class III (i.e sotalol) and class IA (i.e. quinidine), antiarrhthamics, macrolide antibiotics, antipsychotics, TCAs

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4
Q

Endocrin -hot flashes

A

tamoxifen, clomiphene

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5
Q

Endocrin - hyperglycemia

A

Tacrolimus, Protease inhibitors, Niacin, HCTZ, Beta blockers (because remember beta stimulation causes an increase in insulin), Corticosteroids.

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6
Q

Endocrin - hypothyroid

A

lithium, amiodarone, sulfonamides

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7
Q

Endocrin – Acute cholestatic hepatitis, jaundice

A

Erythromycin

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8
Q

Endocrin - Diarrhea

A

Metformin, Erythromycin, Cochicine, Orlistat, Acarbose (might excite colon on accident)

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9
Q

Endocrin - focal to massive hepatic necrosis

A

Halothane, Amanita phalloides (death cap mushroom), Valproic acid, Acetaminophen (HAVAc on the liver)

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10
Q

Endocrin -hepatitis

A

Isoniazid (INH)

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11
Q

Endocrin -Pancreatitis -

A

Didansosine, Corticosteroids, Alcohol, Valproic acid, Azathioprine, Diuretics (furosemide, HCTZ). (Drugs Causing A Violent Abdominal Distress)

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12
Q

pseudomembranou colitis

A

Clindamycin, ampicillin, cephalosporins

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13
Q

hematologic - (A)granulocytosis

A

Dapsone, Clozapine, Carbamazepine, Colchicine, Methimazole, Propylthiouracil (Drugs CCCrush Myeloblasts and Promyelocytes)

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14
Q

hematologic - Aplastic Anemia

A

Carbamazepine, Methimazole, NSAIDS, Benzene, Chloramphenicol, Propylthiouracil (Can’t Make New Blood Cells Properly)

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15
Q

hematologic - Direct Coombs positive hemolytic anemia

A

Methyldopa, penicillin

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16
Q

hematologic - gray baby

A

chloramphenicol

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17
Q

hematologic- Hemolysis in G6PDH

A

INH, Sulfonamides, Dapsone, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin. (hemolysis IS D PAIN)

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18
Q

hematologic- megaloBLASTic anemia

A

Phenytoin, Methotrexate, Sulfa drugs (having a BLAST with PMS

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19
Q

hematologic- Thrombocytopenia

A

Heparin, Cimetidine

20
Q

hematologic- Thrombotic complications

A

OCPs (i.e. estrogens)

21
Q

musc/skin/connective tissue - fat redistribution

A

protease inhibitors, glucocorticoids

22
Q

musc/skin/connective tissue - gingival hyperplasia

A

phenytoin, verapamil, cyclosporine, nifedipine

23
Q

musc/skin/connective tissue -hyperuricemia (gout)

A

Pyrazinamide, Thiazides, furosemide, niacin, cyclosporine (painful Tophi and Feet Need Care)

24
Q

musc/skin/connective tissue -hematologic- myopathy

A

fibrates, niacin, colchicine, hydroxychloroquine, interferon alpha, penicillamine, statins, glucocorticoids

25
Q

musc/skin/connective tissue - osteoporosis

A

corticosteroids, heparin

26
Q

musc/skin/connective tissue -photosensitivity

A

sulfonamides, amiodarone, tetracyclines (5-FU)

27
Q

musc/skin/connective tissue - Rash (STEVENS-JOHNSON syndrome)

A

anti-epileptic drugs (ethosuximide, carbamzazepein, lamotrigine, phentoin, phenobarbital, Allopurinol, sulfa drugs, penicillin)

28
Q

musc/skin/connective tissue -Sle like syndrome

A

Sulfa drugs, Hydralazine, INH, Procainamide, Phenytoin, Etanercept (having lupus is ‘SHIPPE’)

29
Q

Neuro - Cinchonism

A

quinidine, quinine

30
Q

Neuro -Parkinson like syndromes

A

Antipsychotics, Reserpine, Metoclopramide (cogwheel rigidity of the ARM)

31
Q

Neuro -Seizures

A

INH (vit b6 deficiency), Bupropion, Imipenem/cilastatin, Tramadol, Enflurane, Metoclopramide (with seizures, I BITE My tongue)

32
Q

Neuro -Tardive dyskinesia

A

antispychotics, metoclopramide

33
Q

respiratory - pulmonary fibrosis

A

bleomycin, amiodarone, busulfan, methotrexate (breathingair badly from medications)

34
Q

renal/genitourinary - diabetes insipidus

A

Lithium, demeclocycline

35
Q

renal/genitourinary -Fanconi syndrome

A

Expired tetracycline

36
Q

renal/genitourinary -hemorrhagic cystitis

A

cyclophosphamide, ifosfamide (prevent by coadministering with mesna)

37
Q

renal/genitourinary -interstitial nephritis

A

methicillin, NSAIDS, furosemide

38
Q

renal/genitourinary -SIADH

A

Carbamazepine, cyclophosphamide, SSRIs (Can’t Concentrate Serum Sodium)

39
Q

multiorgan - disulfiram like reaction

A

metronidazole, cephalosporins, griseofulvin, procarbazine, 1st generation sulfonylureas

40
Q

multiorgan - nephrotoxicity ototoxicity

A

Aminglcosides, vanomycin, loop diuretics, cisplatin

41
Q

CYP inducers

A

chronic alcohol use, Modafinil, St. John’s wort, Phenytoin, Phenobarbital, Nevirapine, Rifampin, Griseofulvin, Carbamazepine

42
Q

CYP inhibitors

A

acute alcohol abuse, gemfibrozil, ciprofloxacin, Isoniazid, Grapefruti Juice, Quinidine, Amiodarone, Ketoconazole, Macrolides, Sulfonamides, Cimetidine, Ritonavir

43
Q

Sulfa drugs

A

Probenecid, Furosemide, Acetazolamide, Celecoxib, Thiazides, Sulfonamide antibiotics, Sulfasalazine, Sulfonylureas.

44
Q

What are the non-depolarizing paralytics?

A

Atracurium or vecuronium

45
Q

‘prost’

A

Latanoprost

First Aid (33 decks)

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