Autoantibodies Flashcards

1
Q

anti-ACh receptor

A

myasthenia gravis

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2
Q

anti-basement membrane

A

Goddpasture

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3
Q

anti-cardiolipin, lupus anticoagulant

A

SLE, antiphospholipid syndrome

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4
Q

anticentromere

A

Limited scleroderma (CREST syndrome)

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5
Q

anti-desmoglein

A

Pemphigus vulgaris

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6
Q

anti-dsDNA, anti-SMITH

A

SLE

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7
Q

anti-glutamate decarboxylase

A

type 1 DM

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8
Q

anti-hemidesmosome

A

bullous pemphigoid

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9
Q

antihistone

A

drug induced lupus. Classically hydralazine and procainamide.

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10
Q

anti-Jo-1, anti-SRP, anti-Mi2

A

polymyositis, dermatomyositis

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11
Q

antimicrosomal, antithyroglobulin

A

hashimoto thyroditis

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12
Q

antimitochondrial

A

primary biliary cirrhosis

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13
Q

antinuclear antibodies

A

SLE, nonspecific

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14
Q

anti-Scl-70 (anti-DNA topoisomerase 1)

A

Scleroderma (diffuse)

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15
Q

anti-smooth muscle

A

autoimmune hepatitis

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16
Q

anti-SSA, anti-SSB (anto-Ro, Anti-LA)

A

Sjogren syndrome

17
Q

ant-TSH receptor

A

Graves

18
Q

Anti-U1 RNP (ribonucleoprotein)

A

mixed connective tissue disease

19
Q

c-ANCA (PR3-ANCA)

A

Granulomatosis with polyangiitis (Wegener)

20
Q

IgA antiendomysial, igA anti-tissue transglutaminase

A

Celiac

21
Q

pANCA (MPO-ANCA)

A

microscopic polyantiitis, Churg Strauss syndrome

22
Q

AntitopoisimerSe I (scl-70), anticentromere, anti-RNA polymerase III

A

Systemic sclerosis (scleroderma)

22
Q

AntitopoisimerSe I (scl-70), anticentromere, anti-RNA polymerase III

A

Systemic sclerosis (scleroderm