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First Aid > Protooncogenes > Flashcards

Protooncogenes Flashcards

1
Q

What are the Proto-oncogenes (1 hit gain of function)

A

RAS, MYC, ERBB1 (EGFR), ERBB2 (HER2), ABL, BRAF

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2
Q

RAS

A

GTP-binding protein: Cholangiocarcinoma, Pancreatic adenocarcinoma

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3
Q

MYC

A

Transcription Factor: Burkitt Lymphoma

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4
Q

ERBB1 (EGFR)

A

Receptor Tyrosine Kinase. Lung Adenocarcinoma.

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5
Q

ERBB2 (HER2)

A

Receptor tyrosine kinase. Breast Cancer

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6
Q

ABL

A

Nonreceptor tyrosine kinase. Chronic myelogenous leukemia

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7
Q

BRAF

A

Ras signal transduction. Hairy cell leukemia, Melanoma

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First Aid (33 decks)

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