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Pharmacology 1 > Toxicities and Antidotes > Flashcards

Toxicities and Antidotes Flashcards

1
Q

Digitalis toxicity

A 
Lidocaine (class IB)
Digoxin antibodies
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2
Q

Acetaminophen overdose

A

Acetylcysteine

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3
Q

Cholinesterase inhibitors

A

Atropine + Pralidoxime

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4
Q

Quinidine, TCAs

A

Bicarbonate

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5
Q

Fluoride, CCBs

A

Calcium

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6
Q

Iron toxicity

A

Deferoxamine

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7
Q

Caffeine, theophylline, sympathomimetics

A

Esmolol

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8
Q

Methanol, ethylene glycol

A

Ethanol

Fomepizole (Ethanol dehydrogenase antagonist)

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9
Q

Benzodiazepines, Zolpidem

A

Flumazenil

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10
Q

Beta adrenoreceptor blockers

A

Glucagon

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11
Q

Hypoglycemics

A

Glucose

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12
Q

Cyanide poisoining

A

Hydroxocobalamine

inhaled amyl nitrite + IV sodium nitrite + IV sodium thiosulfate

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13
Q

Opioid analgesics

A

Naloxone

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14
Q

Carbon monoxide

A

Hyperbaric Oxygen

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15
Q

Muscarinic reeptor blockers

A

Physostigmine

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16
Q

Organophosphates

A

Pralidoxime

17
Q

Heparin

A

Protamine sulfate

18
Q

Warfarin

A

Vit K, FFP

19
Q

Inorganic lead poisoning

A

Chelation - oral succimer (OPD);

EDTA +/- Dimercaprol severe cases

20
Q

Organic lead poisoning

A

decontamination, seizure control

21
Q

Arsenic poisoning

A

Chelation w/ Dimercaprol

22
Q

Mercury poisoning

A

oral Succimer or IM Dimercaprol

23
Q

Copper toxicity

A

Penicillamine

24
Q

Methotrexate toxicity

A

Leucoverin

25
Q

Cyclophosphamide toxicity

A

MESNA (mercaptoethane sulfate)

26
Q

Doxorubicin toxicity

A

Dexrazoxane

27
Q

Cisplatin toxicity

A

Amifostine

28
Q

Methemoglobinemia

A

Methylene blue

29
Q

Cardiotoxicity from Bupivacaine/ Ropivacaine

A

Intralipid (fat emulsion used in TPN)

30
Q

Lithium toxicity

A

Hemodialysis

31
Q

Clonidine induced rebound tenderness

A

Phentolamine

32
Q

Class IA antiarrythmics drug overdose
(Procainamide, Quinidine, Disopyramide)
drug induce arrythmias

A

Sodium lactate

33
Q

heparin induced thrombocytopenia

A

lepirudin

34
Q

Heparin induced bleeding

A

Protamine sulfate

35
Q

Antidote for thrombolytic overdose

A

Aminocaproic adic/ Tranexamic acid

Pharmacology 1 (17 decks)

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