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Pharmacology 1 > Antiprotozoal drugs > Flashcards

Antiprotozoal drugs Flashcards

0
Q

Blood schizonticides

A

Chloroquine

Quinine

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1
Q

Tissue schizonticide

A

Primaquine

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2
Q

Gametocides

A

Primaquine

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3
Q

Sporonticides

A

Proguanil

Pyrimethamine

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4
Q

Class: antimalarial dmards
MOA: prevents polymerization of heme into hemozoin
Use: malaria (nonfalciparum)
Chemoprophylaxis

A

Chloroquine

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5
Q

Chloroquine SE:

A

Auditory impairment, retinal damage, psychosis

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6
Q

Use: severe falciparum malaria
SE: cinchonism

A

Quinidine

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7
Q

DOC for malaria in pregnant patients

A

Quinine

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8
Q

Headache, tinnitus, vertigo

A

Cinchonism

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9
Q

Complication or P.falciparum

Characterized by intravascular hemolysis, massive hemoglobinuria and acute renal failure

A

Black water fever

Tx quinine

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10
Q

MOA: forms electron transferring redox compounds that act as cellular oxidants
Uses: radical curer of P.Vivax, P.Ovale

A

Primaquine

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11
Q

Used for multidrug resistant malaria

A

Doxycycline

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12
Q

DOC of uncomplicated falciparum malaria in the philippines

A

Artemether-lumefantrine (Co-artem)

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13
Q

Chemoprophylaxis

Chloroquine sensitive area

A

Chloroquine 500 mg/tab 1 tab weekly

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14
Q

Chemoprophylaxis

Chloroquine resistant areas

A

Mefloquine 250 mg/tab 1 tab weekly

Malarone (atovaquone 250 mg/ proguanik 100 mg/ tab 1 tab daily

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15
Q

Chemoprophylaxis for multidrug resistant malaria

A

Doxycycline 100 mg/tab 1 tab daily

Pharmacology 1 (17 decks)

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