Drugs for Amebiasis

Question 1

Tissue Amebicides

Answer 1

Chloroquine, emetines, metronidazole, tinidazole

Question 2

Luminal Amebicides

Answer 2

diloxanide furoate, iodoquinol, paromomycin

Question 3

DOC for Asymptomatic, intestinal infection; Asymptomatic cyst of E. histolytica

Answer 3

Dilaxonide furoate

Question 4

DOC for Mild to moderate intestinal infection

Answer 4

Metronidazole + luminal agent

Question 5

DOC for Severe intestinal infection

Answer 5

Metronidazole or Tinidazole + Luminal agent

Question 6

DOC for hepatic abscess & other extraintestinal disease

Answer 6

Metronidazole or tinidazole + luminal agent

Question 7

DOC for Cryptosporidiosis

Answer 7

Nitazoxanide

Question 8

DOC for prophylaxis & treatment of pneumocystotsis

Answer 8

Co-Trimoxazole

Question 9

DOC for prophylaxis & treatment of toxoplasmosis

Answer 9

Pyrimethamine- sulfadiazine

Question 10

DOC Trypanosomiasis

Answer 10

West african w/ CNS involvement - Eflornithine

East aftrican w/ CNS involvement - Melarsoprol

Question 11

DOC for Chagas disease

Answer 11

Nifurtimox - inhibits trypanothione reductase

Question 12

DOC for Leishmaniasis (except for India)

Answer 12

Sodium Stibogluconate