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Pharmacology 1 > Antifungal Agents > Flashcards

Antifungal Agents Flashcards

0
Q

SE of amphotericin B

A

Nephrotoxic (RTA with magnesium & potassium wasting)

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1
Q

Antifungal MOA- binds to ergosterol in fungal cell membrane forming artificial pores

A

Amphotericin -B

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2
Q

Antifungal used for cryptococcus and chromoblastomycosis

Madura foot

A

Flucytosine

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3
Q

Antifungal DOC: chronic mucocutaneous candidiasis , dermatophytes

A

Ketoconazole

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4
Q

DOC: cryptococcal meningitis (tx & prophylaxis)

A

Fluconazole

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5
Q

Antifungal MOA: inhibits B glucan synthase

Use: disseminated and mucocutaneous candidiasis

A

Caspofungin

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6
Q

MOA: interferes w/ microtubule function

A

Griseofulvin

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7
Q

Antifungal MOA: interferes with ergosterol synthesis by inhibiting fungal squalene oxidase

A

Terbinafine

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Pharmacology 1 (17 decks)

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