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Pharmacology 1 > Antimycobacterial Drugs > Flashcards

Antimycobacterial Drugs Flashcards

0
Q

DOC: drug induced (isoniazid) neurotoxicity

A

Pyridoxine

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1
Q

TB meds
MOA: inhibit mycolic acid synthesis
SE: neurotoxicity & hepatitis, drug induce lupus

A

Isoniazid

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2
Q

MOA: inhibits DNA dependent - RNA polymerase

A

Rifampicin

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3
Q

SE: red orange urine, flu likesymptoms

A

Rifampicin

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4
Q

MOA: inhibits RNA-dependent DNA polymerase

A

Antiretrovirals

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5
Q

MOA: inhibits arabinosyl transferases involve in the synthesis of arabinogalactan
Bacteriostatic

A

Ethambutol

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6
Q

SE: visual disturbance ( red-green color blindness)

A

Ethambutol

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7
Q

SE: most hepatotoxic anti tb med
Hyperuricemia

Sterilizing agent

A

Pyrizinamide

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8
Q

DOC: leprosy

A

Dapsone - inhibits folic acid synthesis

Used in combination with rifampicin & clofazimine

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9
Q

Drugs for Atypical mycobacteria

A

Prophylaxis- clarithromycin or azithromycin with/ without rifabutin in px with CD4 counts less than 50/L

Tx- Azithromycin or clarithromycin w/ ethambutol & rifabutin

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Pharmacology 1 (17 decks)

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