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Ch 32 Secondary GN > THIN BASEMENT MEMBRANE NEPHROPATHY > Flashcards

THIN BASEMENT MEMBRANE NEPHROPATHY Flashcards

1
Q

What is the other name of thin basement membrane nephropathy?

A

• Benign familial hematuria
• Thin GBM nephropathy

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2
Q

What is the typical f inding on renal pathology inTBMN?

A

diffuse thinning of the GBMs

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3
Q

What are the renal biopsy findings in TBMN?

A

LM: no abnormality
IF: no staining (no deposits of Ig/complement)
EM: diffuse & uniform thinning of the GBM

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4
Q

What 2 genes mutations has been linked to TBMN?

A
  1. COL4A3 gene
  2. COL4A4 gene
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Ch 32 Secondary GN (35 decks)

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