SARCOIDOSIS Flashcards

1
Q

The kidney can be affected in Sarcoidosis by?

A

HYPERCALCEMIA

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2
Q

What are the 3 most common renal manifestations of sarcoidosis?

A
  1. GRANULOMATOUS INTERSTITIAL NEPHRITIS
  2. NEPHROLITHIASISS
  3. TUBULAR FUNCTIONAL ABMORMALITIES
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3
Q

What are the 6 glomerular lesions associated with sarcoidosis?

A
  1. MCD
  2. MN
  3. MPGN
  4. FSGS
  5. IgAN
  6. PROLIFERATIVE & CRESCENTIC GN
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4
Q

What is the diagnostic appearance of amyloid fibrils when stained with Congo Red?

A

APPLE GREEN BIREFRINGENCE ON POLARIZED LIGHT

SALMON ON NON-POLARIZED LIGHT

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5
Q

What is the ultrastructural appearance of amyloid fibrils?

A

• nonbranching
• 8-12 nm

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6
Q

All amyloid fibrils contain this glycoprotein

A

SAP (Serum Amyloid Protein)

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