GLOMERULAR LESIONS ASSOCIATED WITH NEOPLASIA

Question 1

What is the commonest lesion associated with carcinoma?

Answer 1

MN

Question 2

What are the 4 CA most commonly associated woth glomerular lesions?

Answer 2

1. LUNG
2. BREAST
3. STOMACH
4. COLON

Question 3

What is the predominant IgG subclasses of the immune deposits in cancer-associated MN

Answer 3

IgG1 and IgG2

Question 4

What is the IgG subclass predominant in idiopathic MN?

Answer 4

IgG4

Question 5

What is the feature typical of primary MN that distinguish it from secondary MN?

Answer 5

Antibodies to the transmembrane glycoprotein M-type PLA2R

Question 6

What are the 2 antibodies associated with MN?

Answer 6

1. PLAR2
2. THSD7A

Question 7

What MN oattern is associated with HD?

Answer 7

MCD or focal glomerulosclerosis

Question 8

What GN pattern is associated with renal cell carcinoma, HD, and CLL?

Answer 8

Secondary amyloidosis (AA type)

Question 9

What is a late pattern in HD?

Answer 9

Renal amyloidosis

Question 10

What most often occurs at the time of initial presentation in HD?

Answer 10

MCD

Question 11

CLL is associated with what GN pattern?

Answer 11

MPGN

Question 12

What are the 3 types of CA associated with HUS?

Answer 12

STOMACH
PANCREAS
PROSTATE