SJOGREN SYNDROME Flashcards
1
Q
What are the 6 serologic abnormalities in Sjögren syndrome?
A
- hypergammaglobulinemia
- rheumatoid factor
- cryoglobulins
- homogeneous or speckled pattern ANA
- anti-Ro/SSA
- anti-La/SSB
2
Q
What is the major clinical renal manifestations of patients with Sjögren syndrome?
A
TUBULOINTERSTITIAL INVOLVEMENT
3
Q
What are the 4 tubular defects in Sjogren syndrome?
A
- DISTAL RTA
- PROXIMAL TUBULAR DEFECTS (rare)
- IMPAIRED CONCENTRATING ABILITY
- HYPERCALCIURIA
4
Q
What are the 4 treatments used in Sjogren syndrome?
A
- CORTICOSTEROIDS
- RITUXIMAB (if with systemic dse)
- BELIMUMAB
- ABATACEPT
