GLOMERULAR DISEASE ASSOCIATED WITH DRUGS Flashcards
1
Q
What is the renal biopsy findings of heroin-associated nephropathy (HAN)?
A
FSGS
2
Q
What is the course of HAN?
A
relentless progression to ESKD over many years in those addicts who continued to use heroin
3
Q
What are the 2 types of renal abnormalities characteristic of NSAID use?
A
ACUTE INTERSTITIAL NEPHRITIS +
NEPHROTIC SYNDROME (MCD)
4
Q
What is the mean time of onset of NSAID-induced nephrotic syndrome
after initiation of NSAID therapy?
A
5.4 months (range 2 weeks to 18 months)
5
Q
What is the most common lesion in D-Penicillamine treatment for rheumatoid arthritis?
A
MN
6
Q
What lesion is associated with Captopril?
A
MN
7
Q
What is substituted for captopril to ameliorate the nephrotic syndrome?
A
ENALAPRIL
8
Q
What 2 drugs are associated with collapsing FSGS?
A
- IFN-α
- PAMIDRONATE
