The Transformation Of Surgery Flashcards

1
Q

What was good and bad about nitrous oxide?

A

It reduced pain but had limited impact as it didn’t knock the patient out

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2
Q

What was good and bad about ether?

A

It made the patient unconscious
sometimes caused vomiting,
tended to irritate the lungs of the patient,
highly flammable – only form of light was artificial light from candles or gas lights,
it produced a very deep sleep which lasted for days,
had to be carried around in large heavy glass bottles which were difficult to carry into the home of the patient

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3
Q

Why did some people oppose using anaesthetic?

A

Religious - some people thought pain was part of gods plan for humans especially child birth, when queen V used it for giving birth to her eighth child in 1853 it became more acceptable
In 1848 hannah greener died while being given chloroform to remove one of her toenails
Anaesthetics encouraged surgeons to go deeper into the body but blood loss and infection had no be solved so the death rate increased
Some surgeons thought an unconscious patient was more likely to die
they didn’t trust them as they were new, and their effects were not fully understood
the number of patients dying increased

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4
Q

What were the things wrong before 1861?

A

They washed their hands in water that may be carrying infection
Instrument table and operating room would not have been cleaned
They would have worn coat with lots of old blood on it to show how experienced they were and as a status symbol
- Before antiseptics were used the use of anaesthetics meant that the operations could take longer and they could do more complex operations, but they did not understand about disease or infection and germs therefore the patient often died many days later due to infection
- They were often carried out in the patients home or hospital ward, this meant the conditions that the operation was carried out in were not hygienic, they would wear ordinary clothes

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5
Q

What were the breakthroughs in infection before 1861

A

Florence nightingale - ensured high hygiene standards among her nurses and insisted each hospital bed had one person
Ignaz semmelwesis - noticed medical students were more likely to kill in birthing ward than nurses, made them wash their hands in chlorinated water

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6
Q

How did they prevent blood loss before 1900

A

Cauterisation - using a hot iron to burn body tissue this sealed blood vessels and stopped bleeding
Ambroise paré - developed metal chips to clip blood vessels or hr tied them shut with silk threads called ligatures these caused infection and did not to the bleeding if they were not tied properly

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7
Q

What were the first anaesthetics?

A

Nitrous oxide and ether

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8
Q

What were the early experiments in blood transfusion?

A

After Harvey’s discovery people tries blood transfusions between sheep and humans, sometimes they were successful because only a tiny amount was transfused most times they were not
Human to human in 1795
Jame Blundell between 1825-30 gave blood transfusions to 10 people only half survived
James Blundell brought blood transfusions to Britain, he developed different kinds of syringes, pumps and tubes but he had three main problems – clotting, blood clots as soon as it left the body, avaliablilty – transfusions could only be done from donor to donor, immune response, transferring from a animals used to destroy human blood cells and often lead to death, red blood cells would clump together

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9
Q

Who discovered blood groups?

A

Karl Landstiener in 1900
He discovered that there was different blood groups and the different blood groups were incompatible because of the antigens on the surface of each blood cell was different therefore the antibodies attacked the foreign antigens
did not have an immediate impacy as the donor still needed to be there.

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10
Q

What were the problems with blood transfusions?

A

Blood would clot

Blood couldn’t be stored and the transfusion had to be done with the person there

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11
Q

What were the advances of blood transfusion during the war?

A
  • In 1915 Richard Lewisohn found that adding sodium citrate stopped blood from clotting and the donor did not have to be there so more transfusions could take place, although the blood cells deteriorated if the blood was not used up soon afterwards
  • Richard Weil found that blood could be stored in refridgerated conditions
  • In 1916 James Turner and Francis Rous found that adding a citrate glucose solution allowed it to be stored for longer, the army could ask for donations and they were available to treat the wound
  • Geoffrey Keynes a british surgeon developed a portable machine
  • First blood o depot was established in 1917 for the battle of Cambrai
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12
Q

What was the impact of war on surgery?

A

Surgeons worked with a variety of wounds this meant that their training was broader
Surgeons gained experience quickly
Surgeons had to improvise this lead to rapid development
Explosive weapons meant soldiers had shrapnel embedded in them this lead to the development of saline to fight infection
First attempts at brain surgery
Plastic surgery was developed
- They had been given more experience as they had to deal with a wide range of injuries, for example they used rubber bands around patients heads to stop the bleeding and they used saline solution to wash out pulped brain they even used magnets to pull out shrapnel
- They suffered deep wounds, which caused infection surgeons found that cutting away infected tissue and soaking the wound with a saline solution was the best way of doing this
- They started doing plastic surgery

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13
Q

What was the impact of communications in surgery?

A

Many surgeons took careful notes and began to publish photographs
More scientists published their ideas in medical journals
Medical conferences started to take place
Newspapers reported notable operations
public was more interested
communicated problems - Hannah Greeners death in the Lancet
only published information that was based on good science

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14
Q

What was the impact of science and technology in surgery? impact of Pasteur

A
  • Carbolic spray, sterilising instruments, wearing rubber gloves, catgut for ligatures, gowns, face maskes, based on pasteurs germ theory
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15
Q

What opposition did lister face?

A

To begin with surgeons were very critical as they didn’t like the smelly and corrosive carbolic acid
Didn’t accept the idea that microbes caused disease as you couldn’t see them without a microscope
Slowed down operations so blood loss became more of a problem
Didn’t copy listers ideas properly and the death rate didn’t change so they didn’t think it worked
Lister kept changing his methods to improve his work so doctors thought he didn’t know what he was doing
Equipment was very heavy and expensive
Some surgeons had good results without carbolic acid
Nurses resented extra work
but by 1890 most operations were carried out under antiseptic conditions

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16
Q

How did lister change surgery?

A

By 1980s antiseptic surgery was common this developed into aseptic surgery were germs were removed from the theatre rather than the wound

17
Q

James Simpson

A
  • James Simpson wanted to discover a better anaesthetic, he invited some other doctors to his house where they experimented by inhaling vapours from various chemicals, his wife found the all unconsciousness and they realised that chloroform was very effective and did not have the negative side effects of ether.
  • Used it in an operation in Endinbourgh in 1847 but it became more widespreaf when Queen Victoria used it for the birth of her eight child,
  • Toom much or too little caused problems, a number of young healthy patients died after inhaling it, this was because it effected the heart however in 1848 John Snow developed an inhaler that regulated the dosage and reduced the number of deaths
  • He was the first man to be knighted for services to medicine and when he died in 1870 30,000 mourners lined the streets of Edinburgh
18
Q

who discovered ether

A
  • Ether – William Morton a dentist in the USA found that the gas ether was a long lasting anaesthetic, used in an operation to remove a growth from a patient’s neck. Robert Liston used it while amputating a leg.
19
Q

Joseph Lister before carbolic acid

A
  • He was appointed professor of surgery at Glasgow uni in 1859 and then became surgeon at Glasgow Royal Infirmary in 1861, he was put in charge of a new building at the hospital and he thought that he could reduce the death rate but that did not happen and between 1861 and 1865 over half the people having operations died
  • He tried various methods of encouraging wounds to heal cleanly without infection but had little success, he became interested in pasteurs work and the idea of microbes being responsible for causing disease, in 1864 he found that carbolic acid was used in the sewage works at Carlisle and it killed parasites so he fought it could be used to kill the microbes causing infection
20
Q

Joseph Lister after carbolic acid

A
  • In 1865 he tested his ideas when an 11 year old boy was brought in with a fracture in his leg, Lister soaked the bandages in carbolic acid and watched the wounds carefully at the end of six weeks it had healed.
  • Lister used this to clean wounds, equipment and bandages and in 1867 he announced that his ward had been sepsis free for 9 months, in 1877 he became professor of surgery at Kings College Hospital in London and carried out an operation on a kneecap in antiseptic conditions
  • Silk did not absorb carbolic acid so could not be sterilised, a thread had to be left dangling out of the wound so the stiches could be pulled out once the wound had healed, he introduced the use of catgut which could be sterilised and this
21
Q

the move from antiseptic to aseptic

A
  • In 1878 Koch made a discovery, steam was more effective at killing the microbes which caused infection, everything could be sterilised by using steam to kill the microbes,
  • The steam steriliser and rubber gloves were part of the shift from antiseptic methods to aseptic conditions where doctors tried to prevent bacteria being anywhere near the wound
22
Q

what was the problem with blood transfusions

A
  • Blood groups got confused, bottles they were stored in were not always free of bacteria, type o worked for everyone but hospitals targeted type o and it became difficult to find donors as it involed cutting deep into the vein, doctors and surgeons were reluctant to change
23
Q

science and tech - importance of x rays

A
  • X rays were discovered by Wilhelm Roentgen in 1895, made surgeons more confident about internal operations
  • People could copy his ideas and they spread very quickly,
  • First x ray machine in 1896 in London Royal Hospital
  • Made it possible to dig out shrapnel without having the dig around in a wound
  • Mobile x ray units in 1st world war
24
Q

Science and technology - development of new surgical equipment

A
  • Chloroform inhaler
  • Carbolic spray
  • Steam steriliser
  • Hypodermic needle – blood transfusions
25
Q

work of Harold Gillies

A
  • Before the first world war French and german surgeons were developing skin grafts techniques using tissue from another part of the body to repair an injury, Gilles was aware of these developments nad asked permission to set up a plastic surgery unit in the British Army
  • He began ways of reconstructing faces to make them as normal looking
  • He kept records and drawing of faces he reconstructed
  • He developed pedicle tubes
  • A narrow layer of skin was lifted up from the body and stitched into a tube at one end, the other end was still attached to the body so blood continued to circulate, when the tube had grown long enough the free end was attached to a new site, once it was in place the pedicle tube could be cut free at the base