The menstrual cycle Flashcards

1
Q

Menstrual cycle

A

refers to the cyclical processes occurring in the female reproductive tract in preparation for pregnancy

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2
Q

Ovary

A

site of ovulation -egg is produced and is intrinsic to the menstrual cycle ad is the reason that the ovary itself produces hormones

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3
Q

Uterine cavity

A

site of endometrium and then woman get menstruation which takes it down through cervix to then the vagina

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4
Q

what is the hormonal control of the menstrual cycle dependent on

A

release of different hormones

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5
Q

4 phases of menstrual cycle

A

1.menstruation
2.the follicular phase, 3.ovulation
4. the luteal phase.

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6
Q

follicular phase

A

post menstruation , hypothalamus release gonadotrophin- releasing hormone activates anterior pituitary releasing the stimulating (FSH) and luteinising hormone(LH)

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7
Q

What do the FSH and LH hormones do in the follicular phase?

A

wake up ovary and produces follicle(dormant egg) one egg will become dominant and supress the others and woman will only stimulate and release egg

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8
Q

folliculogenesis

A

one of the ovams start to grow and gets the ovary to produce estrogen

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9
Q

Theca cells

A

express LH receptors throughout the cycle and synthesise androgens which are transported to granulosa cells which take the androgenand stimulate them and turn them into oestrogen.

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10
Q

Granulosa cells

A

to stop producing other eggs it secrete inhibits to regulate FSH release supress the hormones to ensure only one egg is produced

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11
Q

Oestrogen

A

secretion by developing follicle promotes rapid proliferation in endometrium and stimulates endometrium

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12
Q

what happens after there is rapid proliferation in endometrium

A

Creates positive feedback loop-LH production resulting in LH surge which triggers ovulation

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13
Q

Luteal phase- corupus luteum

A

follicle releases an egg and when follicle releases an egg is supported by. The oestrogen and itself is producing

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14
Q

what happens after follicle releases the egg and produces oestrogen in luteal phase?

A

starts to produce progesterone which helps endometrium itself to prepare for pregnancy.

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15
Q

Progesterone

A

maintains that endometrium at thickness and helps it prepare for pregnancy
forms from the remains of the ovulated follicle and promotes endometrium differentiation by secreting- has negative feedback

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16
Q

Menstruation

A

progesterone stops being produce endometrium sheds away,
fertilization occurs the embryo will begin to implant.

17
Q

Human chorionic gonadotrophin(hCG)

A

produced by the embryo which maintains the corpus luteum.

18
Q

where does the endometrium sit?

A

Endometrium sits inside the uterus

19
Q

what 2 layers does the endometrium compose of?

A

1.base layer: stays same with the cycle
2.functional layer: changes with the menstrual cycle

20
Q

Endometrium surface epithelium

A

bit of the apathy of the endometrium that would face into the cavity of the uterus.

21
Q

Endometrial stroma

A

spaces in between

22
Q

endometrial glands

A

big spaces in between, the glands are big

23
Q

Secretary phase

A

baby implants because glands provide the early nutrients to the baby

24
Q

endometrium cycle 1

A
  1. regeneration:Every month the endometrium sheds away and manages to grow without scarring .Stem cells that go to the endometrium sit there and help generate the scar free healing
25
Q

2 chances of conception

A

changes oestrogen levels
-consistency of the cervical fluid-to allow sperm to go through

26
Q

Decidualisation

A

occurs in response to progesterone-occurs in response to progesterone

27
Q

what are the 3 things decidualisation change how the endometrium looks`/

A

-generates these long glands within the endometrium and builds up glycogen(complex sugar) within the endometrium to feed the baby
-formation of these long spiral arteries-babies need blood supply
Stroma: bits between the gland -round cells are ready for everything
-recruitment of immune cells

28
Q

what are the three things when the fertile window knows the body knows it wants to get pregnant?

A

1.changes the position of the cervix
2.consistency of the cervical fluid changes -go allow the sperm through
3.body temperature increase-because of progesterone

29
Q

Implantation

A

The embryo comes in and fertilisation occurs in the tube and travel down to the uterus and embryo embeds itself within the endometrium

30
Q

Embryo selection

A

interplay between the embryo and the endometrium, place the embryo next to endometrial cells and endometrial cells are growing and the individual cells try reach up and grab the embryo

31
Q

live birth

A

Genetically normal embryo and endometrial function perfectly

32
Q

miscarriage

A

Genetically abnormal embryo endometrium

33
Q

Recurrent miscarriage

A

genetically normal embryo but endometrium doesn’t work

34
Q

Menstruation

A

during this the functional layer breaks down- which is the top layer of the endometrium breaks away .This causes a influx of matric metallic proteases(enzymes that eat tissue and influx of immune cells which eat away whole functional layer of endometrium which then sheds as blood.