The Human Defence System Flashcards
pathogen
an organism that causes disease
immunity
is the ability to resist infection
general defence system definition
acts as a barrier to all pathogens attempting to gain entry to the human body
1st line of general defence system
skin - barrier
lysozyme - enzyme found in sweat etc - bursts wall of bacteria
clotting - helps prevent pathogens getting in
mucous and cilia - in respiratory system traps pathogens
acid - in stomach and vagina kills bacteria
Skin
barrier to infection
prevents pathogens entering
lysozyme
enzyme found in sweat, tears, saliva,
Attacks and dissolved the cell walls of many bacteria (bursts walls of bacteria)
clotting
prevents entry of further pathogens
mucous and cilia
in respiratory system trap pathogens and prevented from entering body.
cilia crest a current moving mucous back up so it can be swallowed
acid
stomach - hydrochloric kills pathogens
vagina - lactic acid prevents growth of pathogens
2nd line of general defence system
destroys pathogens in body
Phagocytic white blood cells - surround and destroy pathogens
Defence proteins -
interferons - produced by cells infected by viruses - prevent the multiplication of virus
complements - 20 proteins found in blood plasma activated by infection, destroy viruses
Inflammation - results in redness, heat, swelling around site of infection - increases number of white blood cells in area
Phagocytic white blood cells
• when cells are damaged by invading micro organisms they release chemicals attracting white blood cells from blood stream
• white blood cells engulf and destroy bacteria/viruses
• these are called phagocytes
• large ones are called macrophages
where can macrophages be
move around in body fluids
remain in fixed places eg: spleen, lymph nodes and other lymphatic tissue eg tonsils, adenoids and appendix
Defence proteins
Complement - 20 proteins found in blood plasma, activated upon infection. destroys viruses and pathogens
Interferons - another set of defence proteins, prevent viral multiplication and help limit spread of virus infections such as colds or influenza
Inflammation
when cells are infected they release a chemical that results in blood capillaries dismaying causing localised swelling, redness and heat
brings more white blood cells to the area to fight infection
inflammation over the whole body?
causes increased body temperature/fever—— interferes with the ability of some bacteria and viruses to reproduce
specific defence system is also called the
immune system
specific defence system
attacks a particular pathogen
production of antibodies
white blood cells destroying infected cells (mono and lympho)
antigen
antigen id a foreign molecule that stimulates the production of antibodies
where are antigens found
they’re found on the surface of pathogens such as viruses and bacteria 🦠
antibody
a protein produced by white blood cells (lymphocytes) in response to an antigen (they inactivate antigens)
antibodies shape
they’re special Y shaped proteins produced by B-lymphocytes in response to antigens