test #4 Flashcards
what type of bacteriophage is capable of integrating its genetic material into the host chromosome and facilitating a horizontal gene transfer via transduction?
a. specialized transducing phage
d. generalized transducing phage
c. heteroduplex phage
d. lytic phage
a. specialized transducing phage
which are present in the highest numbers in the human genome?
a. VNTRs
b. RFLPs
c. TDTs
d. SNPs
d. SNPs
which of the following best describes the formation of an HFR cell?
a. formed by recombination of the F-plasmid into the host cell chromosome at IS sequences
b. begins when lytic phage DNA enters cytoplasm of bacterial cell
c. formed by aberrant excision of the F-plasmid from an HFR cell chromosome
d. formed by rolling-circle replication of bacteriophage genome in the recipient cell cytoplasm
e. formed by integration of a lysogenic bacteriophage genome into host cell chromosome
a
instead of creating a gene map along a chromosome, ____________________ is a method of analysis that detects and locates the genes that, as a group, influence form or appearance
genome-wise association studies (GWAS)
what is the first order of chromatin packing?
a. coiling around nucleosomes
b. looping of 300-nm fibers
c. formation of 300-nm fibers
d. formation of a solenoid
a
the haploid number of chromosomes in one population of mice is 12. if robertsonian translocation occurs in the germ cells of a mouse from this population, how many chromosomes would be present in a gamete?
11
after analysis of 150 pedigrees, the Max from the analysis of linkage between a disease gene D and the DNA marker P was found to be 5.5 at theta=0.015. what is the best interpretation of these results?
evidence supports linkage of d and P at 1.5 cM
where is it more likely to find the DNA sequence encoding the digestive enzyme amylase?
euchromatic region
what describes the inheritance pattern of VNTRs?
codominance
which of the following syndromes is not paired with its causative chromosomal aberration?
a. fragile X syndrome - deletion
b. Down syndrome - Robertsonian translocation
c. Huntington disease - duplication
d. all of these are paired correctly
e. Cri du chat syndrome - deletion
a
does heterochromatin stain darkly or lightly
darkly
which of the following bacterial conjugations would produce a stable partial diploid?
a. F’ x Hfr
b. F’ x F+
c. Hfr x F-
d. F’ x F-
e. Hfr x F+
d
lateral gene transfer can be identified by the presence of DNA sequences that have which of the following characteristics?
a. presence of heteroduplexes
b. differences in G-banding
c. chromosome territories
d. ratio of GC/AT that is highly similar to surrounding sequences
e. ratio of GC/AT that is substantially different than the rest of the genome
e
which of the following is associated with an isochromosome?
a. WAGR syndrome
b. Angelman syndrome
c. Pallister-Killian syndrome
d. DCSR
e. Trisomy 21
c
what is the name of the special type of replication required for F+ cells to donate a copy of F to F- cells?
rolling circle replication
