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test #1 Flashcards

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Biology 101 flashcards
1
Q

which of the following examines all of proteins produced by a cell/organism?
a. transcriptomics
b. translationalomics
c. proteomics
d. genomics
e. metabolomics

A

c. proteomics

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2
Q

what components make up TFIID?
a. TAF and DNA Pol II
b. TBP (x2) and TFIIB
c. TBP (x2) and TAF
d. GTF and TAF
e. TAF and DnaB

A

c. TBP (x2) and TAF

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3
Q

the genotypes of humans are more than 99% similar. what is the term that describes the alternative forms of genes that contribute to human genetic variation?
a. gametes
b. alleles
c. genomes
d. phenotypes
e. isoforms

A

b. alleles

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4
Q

what name is given to the region of a mature, processed mRNA between start and stop codons?
a. 3’ UTR
b. coding region
c. 5’ UTR
d. terminator region
e. promoter

A

b. coding region

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5
Q

which of the following is NOT required for proper splicing of introns in most mRNA molecules
a. adenine branch point about 30 bp upstream of the 3’ end of the intron
b. GU dinucelotide at the 5’ end of the intron
c. AG dinucleotide at the 3’ end of the intron
d. GT dinucleotide at the 5’ end of the preceding exon

A

d

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6
Q

a cell is able to replicate DAN, but it is unable to completely seal the backbones of one of the two strands. which enzyme is likely defective?
a. DNA Pol II
b. ligase
c. DNA Pol I
d. Rho
e. RNA polymerase

A

b. ligase

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7
Q

polyadenylation begins with the binding of ________ near a six-nucleotide mRNA sequence AAUAAA downstream of the stop codon
a. the cleavage and polyadenylationg specificity factor
b. the cleavage-stimulating factor
c. cleavage associated factor I
d. guanylyl transferase
e. polyadenylate polymerase

A

a. the cleavage and polyadenylation specificity factor

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8
Q

in which cellular structure do mRNA codons pair with tRNA anticodons?

A

the ribosome

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9
Q

transcription of inverted repeats produces an mrNA with complementary segments. what type of secondary structure do they form through folding?
a. alpha helices
b. stem-loops
c. GC-rich boxes
d. beta-pleated sheets
e. R-loops

A

b. stem-loops

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10
Q

which of the following uses transcription factors that bind to ICRs within the transcribed region of the gene?
a. RNA Pol
b. RNA Pol III
c. RNA Pol I
d. telomerase
e. RNA Pol II

A

b. RNA Pol III

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11
Q

intrinsic termination of transcription in bacteria requires which of the following?
a. formation of a hairpin in the nascent RNA followed by a string or uracil nucleotides
b. formation of a hairpin in the nascent RNA and the activity of rho protein
c. formation of a hairpin in the nascent RNA followed by a stop codon
formation of a hairpin in the nascent RNA followed by a rut site

A

a. formation of a hairpin in the nascent RNA followed by a string of uracil nucleotides

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12
Q

which of the following I not true of telomerase?
a. ribonucleoprotein because it possess both a protein and an RNA component
b. adds DNA nucleotides to 3’ end of 5’ parental strand
c. reads DNA as a template and synthesizes RNA as a product
d. typically active in cancer cells
e. activity/telomere length have been linked to the aging process

A

c

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13
Q

what enzyme is responsible for transcription of most tRNA genes?

A

RNA pol III

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14
Q

what would most likely occur if a DNA mutation completely deleted an enhancer sequence?

A

transcriptional rate would decrease

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15
Q

which enzyme imitates the 5’ capping of the mRNA?

A

guanylyl transferase

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16
Q

which of the following enzymes/proteins doesn’t break or form bonds?
a. helicase
b. SSB
c. ligase
d. DNA Pol I
e. DNA Pol II

A

b. SSB

17
Q

which regions of a gene are not found within the mRNA transcript

A

promoter and termination regions

18
Q

certain classes of drugs target the enzyme responsible for relaxing DNA super-coding ahead of the replication bubble. which enzyme is being targeted?

A

topoisomerase

19
Q

in the Meselson/Stahl experimental technique, which would be expected following one round of replication? (semiconservative)

A

N14/N15

20
Q

which of the following happens first?
a. 5’ cap added
b. RNA Pol II binds
c. synthesis of pre-mRNA begins at +1
d. TFIIE and TFIIH bind
e. TFIID binds to TATA box

A

e

21
Q

which of the following best describes the enzymatic activity of Torpedo in transcription termination in eukaryotes?

A

5’ to 3’ exonuclease

22
Q

which form of DNA is commonly seen in eukaryotic cells

A

B-form

23
Q

bacterial transcripts often contain more than one coding sequence. what term is used to described RNA molecules such as these that contain multiple units in one RNA molecule?

A

polycistronic

24
Q

which type of RNA base-pairs with pre-edited mRNA to allow the transcript and maybe protein product to be edited?

A

guide RNA

25
Q

what is the full name given to origins of replication in Saccharomyces cerevisiae

A

autonomously replicating sequences

genetics (47 decks)

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