chapter 5 part 1 Flashcards

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1
Q

syntenic genes

A

genes located on the same chromosome

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2
Q

linked genes

A

genes close enough on the same chromosome so they assort together more often than independently

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3
Q

on more closely linked genes, is there more or less crossing over

A

less

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4
Q

what units are used to express the distance between genes

A

map units

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5
Q

max value for recombination frequency

A

50%

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6
Q

why is genetic linkage quantified

A

to map the positions of the genes on chromosomes

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7
Q

homologs that reshuffle produce

A

recombinant chromosomes

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8
Q

homologs that don’t reshuffle produce

A

parental/nonrecombinant chromosomes

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9
Q

genetic linkage mapping

A

plots positions of genes on chromosomes

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10
Q

complete genetic linkage

A

observed when no crossing over occurs between linked genes

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11
Q

is incomplete or complete linkage more common?

A

incomplete

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12
Q

are parental and recombinant types equal?

A

no

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13
Q

does crossing over occur more between genes that are farther apart or closer together

A

farther part

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14
Q

genetic linkage is a _________ relationship among genes located near one another on a chromosome

A

physical

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15
Q

what is recombination between genes accompanied by

A

physical exchange between the homologs - chromosome breakage and rejoining in plants and animals

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16
Q

who showed that crossover is accompanied with breakage and rejoining

A

Creighton and McClintock

17
Q

who first demonstrated that genes are on chromosomes

A

Morgan

18
Q

who was Morgan’s student

A

Alfred Sturtevant

19
Q

what did Alfred Sturtevant use the results of several experiments to create

A

genetic map for 5 X-linked genes in Drosophila

20
Q

what is a map unit also called

A

centiMorgan (cM)

21
Q

recombination hotspots

A

where recombination and crossing over occurs at much higher rate

22
Q

hotspots and cold spots may lead to what

A

placement of genes farther apart or closer together on recombination map than on physical map

23
Q

what may hotspots and cold spots be due to

A

feasibility of DNA in those regions to initiate crossing over

24
Q

recent studies indicate that recombination occurs primarily where?

A

at specific hotspots

25
Q

ex. of organism with complete linkage

A

Drosophila

26
Q

what test is used to detect genetic linkage?

A

two-point test-cross analysis