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Step Review Things to Memorize > Teratogens > Flashcards

Teratogens Flashcards

1
Q

ACEI

A

Renal damage

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2
Q

Alkylating agents

A

absence of digits

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3
Q

Aminoglycosides

A

Ototoxicity

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4
Q

Anti-epilectics

A

Neural tube
cardiac
cleft palate
skeletal (phalanx/nail hypoplasia, facial dysmorph.)

E.g. valproate, cabamazepine, phenytoin, phenobarbitol

High dose folate supp.

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5
Q

DES

A

Vaginal clear cell adenocarcinoma, Müllerian anomalies

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6
Q

Folate antagonists

A

Neural tube defects

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7
Q

Isotretinoin

A

Patients MUST be on contraception

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8
Q

Li

A

Ebstein anomaly

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9
Q

Methimazole

A

1st trimester; aplasia cutis

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10
Q

Tetracyclines

A

Discolored teeth, inhibited bones growth

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11
Q

Thalidomide

A

phocomelia

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12
Q

Warfarin

A

Bone deformities, fetal hemorrhage, abortion, eyes

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13
Q

EtOH

A

Birth defects, intellectual disability, FAS

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14
Q

Cocaine

A

Low birth weight, preterm birth, IUGR, placental abruption

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15
Q

Smoking

A

Low birth weight, preterm labor, placental problems, IUGR, SIDS

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16
Q

Iodine excess or deficiency

A

Cretinism

17
Q

Maternal diabetes

A 
Caudal regression syndrome (anal atresia to sirenomelia)
Heart
Neural tube
Macrosmia
Neonatal hypoglycemia
18
Q

Methylmercury

A

Neurotox

19
Q

Vit A excess

A

Spontaneous abortions, cleft palate, cardiac abnormalities

20
Q

X-rays

A

Microcephaly, intellectual disability

Step Review Things to Memorize (41 decks)

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