Auto-Abs

Question 1

Ach

Answer 1

Myasthenia gravis

Question 2

GBM

Answer 2

Goodpasture sy

Question 3

beta2 glycoprotein

Answer 3

antiphospholipid sy

Question 4

Anticardiolipin, lupus anticoagulant

Answer 4

SLE, antiphospholipid sy

Question 5

Anticentromere

Answer 5

Limited scleroderma (CREST)

Question 6

Desmoglein

Answer 6

pemphigus vulgaris

Question 7

Anti-glutamic acid decarboxylase, islet cell cytoplasmic Abs

Answer 7

T1DM

Question 8

Anti-hemidesmosome

Answer 8

Bullous pemphigoid

Question 9

Antisynthetase (anti-Jo1), anti-SRP and antihelicase (Anti-mi2)

Answer 9

Polymyositis, dermatomyositis

Question 10

Antimocrosomal, antithyroglobulin, anti-thyroid peroxisase

Answer 10

Hashimoto thyroidits

Question 11

Anti-mitochondrial

Answer 11

1˚ biliary cirrhosis

Question 12

Antiparietal cell, anti-IF

Answer 12

Pernicious anemia

Question 13

Antiphospholipase A2-R

Answer 13

1˚ membranous nephropathy

Question 14

Anti-Scl-70 (DNATopoI)

Answer 14

Diffuse scleroderma

Question 15

Anti-smooth muscle

Answer 15

Autoimmune hepatitis type 1

Question 16

Anti-SSA/SSB (anti-Ro and anti-La)

Answer 16

Sjögren sy

Question 17

Anti-TSH-R

Answer 17

Graves disease

Question 18

Anti-presynaptic VGCC

Answer 18

Lambert-Eaton sy

Question 19

IgA anti-endomysial and anti-tissue transglutaminase

Answer 19

Celiac dz

Question 20

MPO-ANCA (p-ANCA)

Answer 20

Microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (Churg-Strauss), UC

Question 21

PR3-ANCA (c-ANCA)

Answer 21

Granulomatosis with polyangiitis

Question 22

Rheumatoid factor IgM to IgG Fc

Answer 22

RA

Question 23

ACPA

Answer 23

More sensitive RA

Question 24

ANA

Answer 24

Non-specific screen SLE

Question 25

Anti-dsDNA, anti-Sm

Answer 25

SLE

Question 26

anti-histone

Answer 26

drug induced lupus

Question 27

anti-U1 RNP

Answer 27

Mixed CT d/o