Auto-Abs Flashcards

1
Q

Ach

A

Myasthenia gravis

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2
Q

GBM

A

Goodpasture sy

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3
Q

beta2 glycoprotein

A

antiphospholipid sy

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4
Q

Anticardiolipin, lupus anticoagulant

A

SLE, antiphospholipid sy

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5
Q

Anticentromere

A

Limited scleroderma (CREST)

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6
Q

Desmoglein

A

pemphigus vulgaris

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7
Q

Anti-glutamic acid decarboxylase, islet cell cytoplasmic Abs

A

T1DM

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8
Q

Anti-hemidesmosome

A

Bullous pemphigoid

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9
Q

Antisynthetase (anti-Jo1), anti-SRP and antihelicase (Anti-mi2)

A

Polymyositis, dermatomyositis

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10
Q

Antimocrosomal, antithyroglobulin, anti-thyroid peroxisase

A

Hashimoto thyroidits

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11
Q

Anti-mitochondrial

A

1˚ biliary cirrhosis

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12
Q

Antiparietal cell, anti-IF

A

Pernicious anemia

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13
Q

Antiphospholipase A2-R

A

1˚ membranous nephropathy

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14
Q

Anti-Scl-70 (DNATopoI)

A

Diffuse scleroderma

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15
Q

Anti-smooth muscle

A

Autoimmune hepatitis type 1

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16
Q

Anti-SSA/SSB (anti-Ro and anti-La)

A

Sjögren sy

17
Q

Anti-TSH-R

A

Graves disease

18
Q

Anti-presynaptic VGCC

A

Lambert-Eaton sy

19
Q

IgA anti-endomysial and anti-tissue transglutaminase

A

Celiac dz

20
Q

MPO-ANCA (p-ANCA)

A

Microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (Churg-Strauss), UC

21
Q

PR3-ANCA (c-ANCA)

A

Granulomatosis with polyangiitis

22
Q

Rheumatoid factor IgM to IgG Fc

A

RA

23
Q

ACPA

A

More sensitive RA

24
Q

ANA

A

Non-specific screen SLE

25
Q

Anti-dsDNA, anti-Sm

A

SLE

26
Q

anti-histone

A

drug induced lupus

27
Q

anti-U1 RNP

A

Mixed CT d/o