TB Flashcards
1
Q
Main bacteria that causes TB
A
- mycobaterium Tuberculosis
2
Q
Explain the TB bacteria
A
- rod shaped
- gram positive bacillus
- acid fast characteristics
3
Q
Explain the cascade of infection
A
- infection inspired
- macrophage engulfs
- profileration in macrophage
- chemoattractants and cytokines released
- macrophage presents antigen to T lymphocyte
- formation of granuloma
4
Q
Testing for TB
A
- sputum culture x3
- early morning urine x3
- biopsies
- culture - ziehl neelson stain
5
Q
Treatment for active TB
A
- 2 months RIPE
- 4 months RI
6
Q
Treatment for latent TB
A
- 3 months RI
OR - 6 months I
7
Q
Treatment of CNS TB (miliary)
A
- 2 months RIPE
- 10 months RI
8
Q
What does RIPE stand for
A
- Rifampicin
- Isoniazid
- Pyramide
- Ethambutol
9
Q
Side effects of rifampicin
A
hepititis
orange/red urine
10
Q
side effects of isoniazid
A
hepitis
fever
neuropathy
11
Q
side effects of pyramide
A
hepatic toxicity
joint pain
12
Q
side effects of ethambutol
A
colour blinding
13
Q
What are the symptoms of TB?
A
- weight loss
- malaise
- cough / haemoptysis
- night sweats
