TB Flashcards
1
Q
define TB
A
this is a mycobacterium infection with M tuberculosis/bovis
2
Q
gram stain of M. tuberculosis
A
gram +ve acid-fast bacilli
3
Q
what does the presence of this mycobacterium cause the formation of?
A
caseating granulomas
4
Q
presentation of TB
A
- night sweats
- haemoptysis
- cough, SOB
5
Q
ghon focus
A
peripheral of the lung, can rupture through visceral pleura
6
Q
assmann focus
A
apical TB lesion (secondary TB)
7
Q
diagnosis of TB
A
- Ziehl-Neelson stain (positive is pink)
- CXR
- bloods
- sputum
- skin prick for latent TB
8
Q
lymph node TB
A
enlarged cervical or supraclavicular nodes
9
Q
biliary TB
A
spreads via the pulmonary vein to the liver, spleen and kidneys
10
Q
active TB management
A
4 drugs for 2 months - rifampicin - isoniazid - pyrazinamide - ethambutol 2 drugs for 4 months - rifampicin - isoniazid
11
Q
latent TB management
A
2 drugs for 3 months - rifampicin - isoniazid 1 drug for 6 months - isoniazid
12
Q
what to use in TB if resistant?
A
streptomycin
13
Q
adverse of streptomycin
A
hearing problems
14
Q
adverse of rifampicin
A
orange tears and urine
15
Q
adverse of isoniazid
A
peripheral neuropathy
hepatitis
