4th Year Pulmonary Fibrosis Flashcards
1
Q
what is nintedanib?
A
monoclonal Ab used in IPF targeting tyrosine kinase
2
Q
what is pirfenidone?
A
antifibrotic and anti-inflammatory
3
Q
drug causes of pulmonary fibrosis
A
amiodarone
cyclophosphamide
methotrexate
nitrofurantoin
4
Q
secondary causes of pulmonary fibrosis
A
alpha-1 antitrypsin deficiency
RA
SLE
systemic sclerosis
5
Q
malt workers lung
A
mould on barley
6
Q
what is Lofgren’s syndrome?
A
sarcoidosis triad
7
Q
what is chylothorax?
A
lymph with fat
8
Q
what is alpha-1-antitrypsin?
A
glycoprotein that is PAS +ve and diastase resistant
9
Q
what is the PAS stain?
A
stains structures high in carbohydrate such as glycogen, glycoproteins, proteoglycans and glycolipids