4th Year Pulmonary Fibrosis Flashcards

1
Q

what is nintedanib?

A

monoclonal Ab used in IPF targeting tyrosine kinase

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2
Q

what is pirfenidone?

A

antifibrotic and anti-inflammatory

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3
Q

drug causes of pulmonary fibrosis

A

amiodarone
cyclophosphamide
methotrexate
nitrofurantoin

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4
Q

secondary causes of pulmonary fibrosis

A

alpha-1 antitrypsin deficiency
RA
SLE
systemic sclerosis

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5
Q

malt workers lung

A

mould on barley

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6
Q

what is Lofgren’s syndrome?

A

sarcoidosis triad

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7
Q

what is chylothorax?

A

lymph with fat

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8
Q

what is alpha-1-antitrypsin?

A

glycoprotein that is PAS +ve and diastase resistant

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9
Q

what is the PAS stain?

A

stains structures high in carbohydrate such as glycogen, glycoproteins, proteoglycans and glycolipids

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