TB 4 - Mx

Question 1

Active TB

• if sev unwell, ? may be needed, must be in ? pressure ? room with ? precautions
• otherwise - refer to specialist TB service within ? weeks: don’t delay while awaiting confirmation if results are highly suggestive
• assess RF for ? TB -> prev TB trt, from ? areas, ? with MDR-TB, poor ? to current trt, aged ?-?, ? co-infection -> if suspected, assess with ?

Answer 1

admission
neg
side
droplet
2
MDR
endemic
contacts
adherence
25-45
HIV
PCR

Question 2

Active TB

• usual ABx drug regimen is ? months of ?(with ?) and ?, supplemented in first ? months with ? and ?
• if CNS inv -> continue the ? and ? for ? months
• coordinated through specialist team and key worker -> monitors ?, clinical ? and any ? effects
• if thought to be high risk of poor adherence -> may have ? ? ? by key worker

Answer 2

6
isoniazid
pyroxidine
rifampicin
2
ethambutol
pyrazinamide
isoniazid
rifampicin
12
adherence
response
adverse
directly observed therapy

Question 3

If Dx confirmed - TB is a ? disease

• all ? members and close contacts should be ? and assessed for ? TB - or if Sxatic, ? TB
• casual contacts (like work colleagues) should be traced only if pt is particularly ? (if ?% or more of close contacts develop TB) OR if casual contacts are at increased risk of infection eg ? workers, people with ?

Answer 3

notifiable
household
traced
latent
active
infectious
10
hcare
HIV

Question 4

MDR-TB

• continue ? control measures until ?/? disease has been excluded
• treat with at least ? drugs of which it is ? to

Latent TB
-treat with ? months of ? and ?(with ?)

Answer 4

infection
laryngeal/pulmonary
6
sensitive

3
rif
isoniazid
pyroxidine

Question 5

Drug SEs
rifampicin - abnormal ?s, ? urine
isoniazid - peripheral ?/?, v rare when prophylactic ? is co-prescribed
pyrazinamide - ?toxic (rare but severe)
ethambutol - ? neuritis, assess with ? ? testing

Answer 5

LFTs, pink
neuropathy, encephalopathy, pyridoxine
hepatotoxic
optic, colour vision