TB 2 - Post-primary (2*) TB Flashcards
1
Q
Mtb re-infection in ?-sensitive individuals
- can be from ? sources or more commonly ? from a ? primary complex
- there is an immediate ? response to disease, thus regional ? inv is ? common
A
tuberculin exogenous reactivation healed granulomatous lymph not
2
Q
- in lung, this creates a classical ? lesion termed an ? focus, with destruction of lung ? leading to ?
- this may ? with fibrosis and ? if the ? system is strong - or will progressively enlarge if immunity is ?
- this has greater risks of eroding into ?/? and causing the complications described in Sxatic primary TB
A
apical assmann parenchyma cavitation heal calcification immune poor vessels/airways
3
Q
Sx
- earliest are non-specific - ?, ? sweats, ?, ? loss
- specific ones are late in established disease -> ? ? cough, repeated small ?, ? pain
- can presx with ? or pleural ?
- O/E there may only be a ? and ? crepitations, with late signs of ? or pleural effusion
- may be ? in advanced disease
A
malaise night anorexia weight prod mucoid haemoptysis pleural pneumonia effusions fever apical consolidation clubbed
4
Q
Either in prim or post prim TB, release of ? ? into the main ? allows them to coughed in the ? in droplets
Dx is freq made with pre-Sx ?
high risk = born in ? areas, prev treated for ?, who has ? ? with TB, ? co-morbs or drugs, who live in ? conditions or are ?/? abusers, or if have ?
A
tubercle bacilli bronchus atmosphere CXR endemic TB close contacts immunosuppressive overcrowded alc/drug HIV