Interstitial lung disease - background and presx

Question 1

The interstitium is the tissue that lies between the ? and pulmonary ?

Answer 1

alveoli

capillaries

Question 2

Interstitial lung disease: generic term used to describe a number of conditions that
diffusely affect the lung ?, sharing certain common features;
? exogenous/ endogenous stimuli.
Chronic ?.
? of the interstitium.
? lung disease.

Answer 2

parenchyma
repeated
inflam
fibrosis
restrictive

Question 3

Aetiology;
Secondary to exogenous stimuli;
o ?/ Environmental: ?, silicosis, ? dust
inhalation.
o Drugs: n..?, a..?, s..?, m..?.
o Hypersensitivity reactions: extrinsic allergic ?.
o Infections: ??, ?/viral infections.

Answer 3

occ
asbestosis
coal
nitrofurantoin
amiodarone
sulfasalazine
mtx
alveolitis
TB
fungal

Question 4

Secondary to endogenous stimuli (? disorders);
o ?osis.
o ? arthritis.
o CTDs: ???/ systemic ?/ ?’s.

Idiopathic;
o Idiopathic pulmonary ?.
• Most common cause of interstitial lung disease.

Answer 4

systemic
sarcoidosis
rheum
SLE
sclerosis
sjogren's

fibrosis

Question 5

Classical clinical features are ? on exertion and a non-productive ‘?’ cough.
On examination;
Inspection: May be signs of ? ?, can be ?.
Palpation: Reduced ?.
Percussion: Normal unless ?pathology.
Auscultation: ‘? end-?crackles’, sometimes expiratory ?.
There may also be signs of ?, i.e. signs of pulmonary
? and ? heart failure.
? spirometry with reduced ????.

Answer 5

SOB
dry
resp distress
clubbed
expansion
secondary
fine
inspiratory
wheeze
decompensation
HTN
r
restrictive
DLCO

Question 6

Idiopathic pulmonary fibrosis (IPF);

Classically onsets in the late ?s, more common in ?.
Aetiology unknown, with ?, chronic ?, ? and
infections stipulated to play a part.
Along with the ? cough and ? dyspnoea, patients will report ? and weight loss, with ?.

Answer 6

60s
males
smx
aspiration
antideps
dry
exertional
malaise
arthralgia

Question 7

Idiopathic pulmonary fibrosis (IPF);
The history should attempt to exclude ? exposures and
? ? diseases.
On examination, there will be fine end-? crackles and also can be ? with finger clubbing.
- Complications are type ? respiratory failure, pulmonary ? and increased risk of ? ?

Answer 7

occ
conn tissue
inspiratory
cyanosis
2
htn
lung ca