TB 1 - Primary TB

Question 1

Infection with ? tuberculosis mainly affects the lungs, ? and ?

Answer 1

mycobacterium
LNs
gut

Question 2

Primary TB

• syndrome is produced by Mtb infection in those who are not ? ?
• there is a mild ? response at infection site followed by spread to ? LNs
• common sites of primary inf are sub-? in the ?-zones of the lungs, in the ? or in the ? ileum
• infection will then spread to ?, ? or ? nodes

Answer 2

prev affected
inflam
regional
pleural
mid
pharynx
terminal
hilar cervical mesenteric

Question 3

• The combo of infective ? and LN inv is known as the primary ?
• in the lung the infective focus is called a ? ?
• ? weeks after infection, with the onset of ? sensitivity, the tissue reaction at both sites of the primary complex changes to form characteristic ? ?omas
• normally these heal with ? and freq ? without therapy

Answer 3

focus
complex
ghon focus
1-2
immune
caseating granulomas
fibrosis
calcify

Question 4

• pts usually are ? , or have a single enlarged LN that may be palpable if ?
• viable ? may remain within - walled off in the ? complex - giving ? TB
• several ways by which primary TB can be sxatic
• these are all more common in pts with ? ?

Answer 4

aSx
cervical
bacteria
primary
latent
incomplete immunity

Question 5

Ways it is Sxatic…

• the ? focus can erode through the ? pleura to discharge organisms and cause TB ?/pleural ?
• enlarged ? LNs can cause ? obstruction and ?
• the hilar LN can ? into the bronchus and ?, causing TB broncho-?
• the enlarging nodes can also erode into ?, giving ? dissemination to the lung via ? arteries, or ? dissemination via ? veins
• ? ? is also common in primary disease

Answer 5

ghon
visceral
pleurisy
effusions
hilar
bronchial
collapse
erode
rupture
pneumonia
vessels
miliary
pulm
systemic
pulm
eryth nod