T2 L10 Physiology of vision Flashcards
How is focus varied?
Changing shape & power of the lens
What does the ray bending?
Cornea does 2/3
Lens does other 1/3 & allows focus to vary (accommodation)
What is hypermetropia?
Long sightedness
Eyeball is too short or lens system too weak
How is hypermetropia corrected?
Converging lens
What is myopia?
Short sightedness
Eyeball is too long or lens system too strong
How is myopia corrected?
Add diverging lens
What is the refractive power of a lens measured in?
Dioptres
Reciprocal of focal length in metres
2D spectacle has focal length of 0.5m
What is the consequence of vertebrate retina evolving back to front?
Ganglion cells & blood vessels are in light path to photoreceptors except in fovea
What are the 3 direct processing layers?
Receptors
Bipolar cells
Ganglion cells
What are the 2 transverse processing layers?
Horizontal cells
Amacrine cells
What happens when a proton hits rhodopsin molecule?
Retinal flips from 11 cis to all trans
Leads to biochemical events resulting from the electrical change (hyper polarisation) in the cell membrane
What do ganglion cells respond strongly & weakly to?
Weakly to changes in overall light intensity
Strongly to local contrast i.e. light on a dark background or dark on a light background
What is the basic response pattern?
Either on centre or off centre
On cells are stimulated by stimulus in centre & inhibited by stimulus in surrounding
Off cells are inhibited by stimulus in centre & stimulated by stimulus in surrounding
What is the sensitivity of red cones?
560nm
What is the sensitivity of green cones?
530nm
What is the sensitivity of blue cones?
420nm
What is the sensitivity of rods?
500nm
What is the most frequent type of cone?
Red cone then green cone then blue cone
What is the spacing between cones?
2.5 micrometers which corresponds to angle of 0.5 minutes of arc
What is colour blindness?
Loss or modification of one of the 3 pigments
What genes are on the X chromosome?
Genes for red & green pigment
What chromosome is the gene for blue pigment?
Chromosome 7
What is central achromatopsia?
Rarer kind of colour blindness
Caused by damage to cortical colour processing areas (V4)
Where do optic tracts relay?
In lateral geniculate nucleus of thalamus
A part goes to superior colliculus in midbrain
Where does the output of the lateral geniculate nucleus go to?
Striate cortex in occipital lobe (V1)
Describe columnar organisation in primary visual cortex
Outer dominance column
Smaller orientational columns
Colour blobs
Describe smaller orientational columns
Orientation of optimal stimuli various systemically across surface
Describe colour blobs
Colour information kept separate from orientation
Passed on to other regions e.g. V4
What are some causes of partial visual loss?
Left eye blindness
Homonymous hemianopia
Bitemporal hemianopia
Scotoma
What are the causes of scotoma?
Retinal damage
Lesions in visual cortex
Pressure from tumours restricting optic nerve, chasm, optic tract or optic radiation
Where does the dorsal stream go and what is it for?
From occipital to parietal cortex
Location
Motion
Action
Where does ventral stream go and what is it for?
From occipital to temporal cortex
Object & face identity
Conscious perception
What is visual agnosia?
Person can see but can’t recognise or interpret visual information due to disorder in parietal lobes
What is visual ataxia?
Person can’t describe but can’t act
What is prosopagnosia?
Inability to recognise familial faces
Associated with damage to specific parts of temporal lobe such as fusiform gyrus on underside of lobe
What causes blindsight?
Destruction of striate cortex leading to blindness in part o visual field corresponding to damaged area
Individuals not aware of stimuli within blind field but if forced to guess they can perform some discrimination tasks & point accurately to locations of stimuli (blindsight phenomena)
What is the vestibulo-occular reflex?
Stabilises gaze by countering movement of head
What is optokinetic reflex?
Stabilises image of moving object on retina
What is pupillary reflex?
If one eyes is illuminated, both will contract as both pretectal & Edinger Westphal nuclei receive signals from both eyes