T1 L3 Topography of the brain Flashcards
What is neurulation?
Formation of the embryonic neural plate & its transformation into the neural tube
What is the notochord?
Small flexible rod made from cells of the mesoderm
What do neural crest cells differentiate into?
Neurons & glia of sensory & autonomic nervous systems
Cells of adrenal gland
Epidermis
Skeletal / connective tissue of the head
What does the mantle layer become?
Brain parenchyma
What happens to the ependymal layer?
Lines ventricles
What is anencephaly?
Failure of anterior neuropore to close
Fatal
Entire forebrain is exposed
How common is anencephaly?
1 in 1000 pregnancies
What is spina bifida?
Failure of posterior neural tube to close
Causes open vertebral canal
Occulta - hidden, vertebral arch defect only
Cystic - meningocele - meninges projects out
How common is spina bifida?
1-2 in 1000 pregnancies
What does the prosencephalon vesicle form?
Forebrain
What does the mesencephalon vesicle form?
Midbrain
What does the rhombencephalon vesicle form?
Hindbrain
What primary vesicle forms the forebrain?
Prosencephalon
What primary vesicle forms the midbrain?
Mesencephalon
What primary vesicle forms the hindbrain?
Rhombencephalon
What does the telencephalon vesicle form?
Cerebral hemispheres
What does the optic vesicles form?
Eyes
What does the diencephalon vesicle form?
Thalamus / hypothalamus
What does the metencephalon vesicle form?
Pons / cerebellum
What does the myelencephalon vesicle form?
Medulla
What secondary vesicle forms the cerebral hemispheres?
Telencephalon
What secondary vesicles forms the eyes?
Optic vesicles