T/B cell function

Question 1

What binds to the lower most part of an antibody?

Answer 1

Macrophage=>Fc Receptor

Question 2

Complement binds to the?

Answer 2

complement binding site on the Fc region (above Macrophage binding)

Question 3

Fc is?

Answer 3

Constant
ƒ Carboxy terminal
ƒ Complement binding
ƒ Carbohydrate side chains

Question 4

Fab is?

Answer 4

Fragment, antigen binding

Question 5

IgA is most commonly found in?

Answer 5

GI tract or Gut infections

Question 6

What does IgE do when it sees an allergen?

Answer 6

Cross-links

Question 7

What are the acute phase reactants?

Answer 7

C-reactive protein
Ferritin
Fibrinogen
Hepcidin
Serum amyloid A

Question 8

acute phase reactants are up or down regulated in inflammation?

Answer 8

Upregulated

Question 9

What does C3b do?

Answer 9

Opsonization (Binds to Bacteria)

Question 10

What does C3, 4, 5 a do?

Answer 10

anaphylaxis

Question 11

C5a?

Answer 11

Neutrophil chemotaxis

Question 12

What stimulates increase in acute phase proteins?

Answer 12

IL-6

Question 13

IL-8?

Answer 13

Chemotactic factor neutrophils

Question 14

IL-1 another name?

Answer 14

osteoclast-activating factor.

Question 15

What inhibits inflammatory response?

Answer 15

IL-10 and TGF-ß