Innate vs Adpative Immunity Flashcards
1
Q
Adaptive immunity consists of?
A
T cells, B cells and circulating antibodies
2
Q
Adaptive immunity MOA?
A
VDJ recombination
3
Q
Adapative immunity is shorter or longer? Robust or Not robust?
A
Longer and more robust
4
Q
What protein does Adaptive immunity secrete?
A
Immunoglobulins
5
Q
Key feature in pathogen recognition of innate immunity?
A
Toll-Like Receptors=>Recognizes PAMP like LPS FLagellin and ssRNA
6
Q
Toll-Like Receptors upregulate?
A
NF-kB
7
Q
MHC class I presents what kind of antigens?
A
Endogenous antigens (like viral and cytosolic proteins) to CD8+ cytotoxic cells
8
Q
MHC class I MOA?
A
Antigen=>TAP=>RER
9
Q
MHC class I has?
A
B2 microglobulin
10
Q
MHC class 2 is present in all?
A
APCs
