Systems (neonatal and childhood illness)

Question 1

neonatal manifestions:

Classic triad: chorioretinitis, hydrocephalus, and intracranial calcifications

Maternal manifestations:

usually asymptomaitc, lymphadenopathy (rarely)

what is teh agent and mode of transmission

Answer 1

• Toxoplasma gondii
• cat feces or ingestion of undercooked meat

Question 2

neonatal manifestions:

Classic triad: PDA (or pulmonary artery hypoplasia) cataracts, adn deafness +/- blueberry muffin rash

Maternal manifestations: rash lymphadenopathy, arthritis

what is the agent and mode of transmission

Answer 2

• Rubella
• Resiratory droplets

Question 3

neonatal manifestions: hearing loss, seizures, petechial rash, blueberry muffin rash

Maternal manifestations: Usually asymptomaticl mononucleosis-like illness

what is the agent and mode of transmission

Answer 3

• CMV
• Sexual contact, organ transplants

Question 4

neonatal manifestions: Recurrent infections, chronic diarrhea

Maternal manifestations: Variable presentation depending on CD4+ count

what is the agent and mode of transmission

Answer 4

• HIV
• Sexual contact, needlestick

Question 5

neonatal manifestions: Encephalitis herpetic (vesicular lesion)

Maternal manifestations: Usually asymptomatic herpetic (vesicular) lessions

what is the agent and mode of transmission

Answer 5

• HSV-2
• skin & mucous membrane contact

Question 6

Neonatal manifestions: Often results in still birth, hydrops fetalis, if child survives, presents with facial abnormalitis (notched teeth, saddle nose, short maxilla) saber shins, CN VIII deafness

Maternal manifestations: Chancre (1o) and dissmeniated rash (2o) are the 2 stages likey to result in fetal infection

what is the agent and mode of transmission

Answer 6

• Syphillus
• Sexual contact

Question 7

Clinical presentation

Vesicular rash on palms and soles; vesicles and ulcers in oral mucosa

What is the agent and associated syn/disease

Answer 7

• Coxsackievirus type A
• hand-foot-mouth disease

Question 8

Clinical presentation

A macular rash over body appears after several days of high fever; can present with febrile seizures; usually affects infants

What is the agent and associated syn/disease

Answer 8

• HHV-6
• Roseola

Question 9

Clinical presentation

A paramyxovirus; beginning at head and moving down, rash ins preceded by cough, coryza, conjuntivitis, and blue-white (koplik) spots on buccal mucosa

What is the agent and associated syn/disease

define morpholoy of virus (ss/ds, etc)

Answer 9

• Measles virus
• Measles (rubeola)
  
  • paraymyxovirus: enveloped, SS - linear, nonsegmented, helical

Question 10

Clinical presentation

Slapped cheek rash on face (can cause hydrops fetalis in pregnant women)

What is the agent and associated syn/disease

ID the morphology of the virus

Answer 10

• B19 virus
• Erythema infectiosum (5th disease)
  
  • DNA, Non enveloped, ss linear -

Question 11

Clinical presentation

Rash begins at head and moves down –> fine truncal rash, postauricular lymphadenopathy (dylan had this)

What is the agent and associated syn/disease

Answer 11

• Rubella virus
• Rubella
  
  • Togavirus, Enveloped, ss + linear icosahedral

Question 12

Clinical presentation

Eryhtematous, sandpaper-like rash with fever adn sore throat

What is the agent and associated syn/disease

Answer 12

• Streptococcus pyogenes
• Scarlet fever

Question 13

Clinical presentation

Vesicular rash begins on trunk, speards to face and extremities with lesions of diff ages

What is the agent and associated syn/disease

Answer 13

• Chickenpox
• VZV
  
  • Herpesvirus, enveloped, DS linear