Anti-microbials (general) Flashcards

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1
Q

Name the drugs that target

peptidoglycan synthesis

A
  • Glycopeptides
    • Vancomycin
    • Bacitracin
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2
Q

Name the drugs that target

peptidoglycan cross-linking

A
  • Penicillins
    • penicillinase-sensitive
    • penicillinase resistant
  • Anti-pseudomonals
  • Cephalosporins (I-V)
  • Carbapenems
  • Monobactams
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3
Q

Name the drugs that are:

Penicillinase-sensitive penicillins

A
  • Penicillin G, V
  • Ampicillin
  • Amoxicillin
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4
Q

Name the drugs that are

Penicillinase-resistant penicllins

A
  • Oxacillin
  • Nafcillin
  • Dicloxacillin
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5
Q

Name the drugs that are

Cephalosporins (I-V)

A
  • 1st: cephazolin
  • 2nd: cefoxitin
  • 3rd: Ceftriaxone
  • 4th: Cefipime
  • 5th: Ceftaroline
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6
Q

Name the drugs that are

Anti-pseudomonal

A
  • Ticarcillin
  • Piperacillin
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7
Q

Name the drugs that are

Carbapenems

MEDI

A
  • Meropenem
  • Ertapenem
  • Doripenem
  • Imipenem
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8
Q

Name the drugs that are

Monobactams

A

Aztreonam

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9
Q

Name the drug class

DNA topoisomerases

A
  • Fluoroquinolones
  • Quinolone
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10
Q

Define the drugs in the following class

Fluoroquinolones

A
  • Ciprofloxacin
  • Levofloxacin
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11
Q

Define the drugs in the following class

Quinolone

A

Nalidixic acid

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12
Q

Define the drugs that

Damage DNA

A

Metronidazole

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13
Q

Define the drugs that target

Folic acid synthesis (DNA methylation)

A
  • Sulfonamides (PABA–>DHF)
  • Trimethoprim (DHF–>THF)
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14
Q

Name the drugs that in the following class

Sulfonamides

A

Folic acid synthesis (DNA methylation)

  • Sulfamethoxazole
  • Sulfisoxazole
  • Sulfadiazone
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15
Q

Name the drugs that are

inhibit mRNA sythesis (RNA polymerase)

A

Rifampin

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16
Q

Name the drugs that target protein synthesis

50S subunit

30S subunit

A
  • 50S subunit
    • Macrolides
    • Stretopgramins
    • Chloramphenicol
    • Clindamcin
    • Linezolid
  • 30S subunit
    • Aminoglycosides
    • Tetracyclines
17
Q

Name the drugs in the following class (and func)

Macrolids

ACE

A

Target 50S subunit

  • Azithromycin
  • Clarithromycin
  • Eryhtromycin
18
Q

Name the drugs in the following class (func)

Streptogramins

DQ

A
  • Dalfopristin
  • Quinupristin
19
Q

name the drugs in the following class (func)

Aminoglycosides

TANG-S

A

inhibit 30S subunit

  • Tobramycin
  • Amikacin
  • Neomycin
  • Gentaomicin
  • Streptomycin
20
Q

name the drugs in the following class (func)

Tetracyclines**

TDM

A

inhibit 30S subunit

  • Tetracylcine
  • Doxycycline
  • Minocycline