Systems (bugs affecting un-immunized children)

Question 1

Rash

• Beginning at head and moving down; rash preceded by c_ough, coryza, conjunctivitis, and blue-white koplik spots on buccal mucosa_
• Beginning at head and moving down with postauricular lymphadenopathy

Answer 1

• **Measles virus **(Rubeola)
  
  • RNA, Paramyxovirus; enveloped, ss - linear nonsegmented helical
• Rubella virus
  
  • RNA, togavirus: enveloped, ss + linear, icosaedral

Question 2

Meninitis

Microbe colonizes nasopharynx can alos lead to myalgia and paralysis

(2)

Answer 2

• H. influenzae type B
• Poliovirus

Question 3

Epiglottitis

Fever w/dysphagia drooling and difficulty breathing due to edematous ‘cherry red’ epiglottis; thumbprint sign on x-ray

Answer 3

H. influenzae type B (also capable of causing epiglottitis in full immunized children)

Question 4

Pharyngitis

Grayish oropharyngeal exudate, psuedomembranes may obstruct airway painful throat

Answer 4

**Corynebacterium diphtheriae **

(elaborates toxin that causes necrosis in pharynx, cardiac, and CNS tissue)