Surgery Rotation 11 Flashcards
Gastric varices are often caused by what?
Splenic vein thrombosis
What should you be concerned about if you treat H. Pylori with triple therapy and pain does not improve?
Zollinger Ellison (gastrin-secreting tumor)
Test for Zollinger Ellison
Secretin stimulation test = gastrin levels remain high after administration of secretin
Tx of Zollinger Ellison
Surgical resection of tumor (most likely in pancreas even though ulcers are in duodenum)
What else should you be looking for with Zollinger Ellison
MEN1
- Pituitary tumors (prolactin or GH)
- Pancreatic endocrine tumors (Zollinger-Ellison syndrome, insulinomas, VIPomas, glucagonomas)
- Parathyroid adenomas
Diff in tx of pt with acute onset vs gradual onset hypovolemic hypernatremia
acute = D5W
Gradual = D5W 1/2NS (pt has adjusted to hypernatremia so you can’t correct too quickly)
What is SMA syndrome?
- When the 3rd part of the duodenum (transverse section) gets compressed between the SMA and aorta
- Due to decrease in aortomesenteric angle
- This blocks food from passing from duodenum to jejunum, causing intestinal obstruction
Tx of SMA syndrome
Restore weight and nutrition
How do diagnose pancreatitis
- Increased amylase + lipase
- CT
Tx of pancreatitis
- Mostly supportive
- NG suction if nauseous, NPO for bowel rest, IV hydration, observation
Common complications of pancreatitis
Psuedocysts (no cells), hemorrhage, abscess, ARDS
What is Courvoisier’s sign
Large, nontender GB, itching and jaundice
Indicative of pancreatic cancer at head of pancreas
What is Trousseau’s sign associated with pancreatic cancer
Migratory thrombophlebitis
Diagnosis of pancreatic cancer?
Endoscopic US and FNA biopsy
When is a pancreatic tumor deemed “resectable”
No mets outside abd, no extension into SMA or portal vein, no liver mets, no peritoneal mets
What is the presentation associated with insulinoma
Whipple’s triad:
- Sxs (sweat, tremor, hunger, seizures)
- BGL < 45
- Sx resolve with glucose administration
What labs indicated real insulinoma vs. exogenous insulin administration
Labs: elevated insulin, C-peptide, and pro-insulin