Psych 3 Flashcards

1
Q

Major side effect of 1st gen antipsychotics

A

Extrapyrimidal sx:

  • Dystonia (spasms) of face, neck, tongue
  • Parkinsonism (resting tremor, rigidity, bradykinesia)
  • Akathisia (restlessness)
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2
Q

Difference in side effects between high potency and low potency FGA

A

High potency = more extrapyrimidal side effects

Low potency = more anticholingeric and antiadrenergic side effects

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3
Q

Major side effect of 2nd gen antipsychotics

A

Metabolic syndrome:

Increased BP, increased blood sugar, excess body fat, abnl cholesterol

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4
Q

DSM Criteria of Schizoaffective Disorder

A
  • Meet criteria for either a major depressive or manic episode during which psychotic sx consistent with schizophrenia are also met
  • Delusions or hallucinations for 2 weeks in the absence of mood disorder sx (to differentiate from mood disorder with psychotic features)

Laymens terms: Mood episodes and active symptoms of schizophrenia occurring at the same time + at least 2 week lifetime history of delusions or hallucinations in the absence of prominent mood symptoms
Aka normal schizo sometimes and schizo + mood at other times

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5
Q

DSM criteria and time frame for delusional disorder

A
  • One or more delusions for at least 1 month
  • Does not meet criteria for schizophrenia
  • Functioning in life not significantly impaired and behavior not obviously bizarre
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6
Q

Average age of onset of delusional disorder

A

After age 40

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7
Q

Delusion that another person is in love with the individual

A

Erotomanic type of delusional disorder

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8
Q

Delusions of having great talent

A

Grandoise type of delusional disorder

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9
Q

Physical delusions

A

Somatic type of delusional disorder

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10
Q

Delusions of being persecuted

A

Persecutory type of delusional disorder

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11
Q

Delusions of unfaithfulness

A

Jealous type of delusional disorder

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12
Q

Tx of delusional disorder

A

Difficult to treat

Antipsychotics, supportive therapy

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13
Q

Intense anxiety that penis will recede into body, possibly leading to death

A

Koro

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14
Q

Sudden unprovoked outburts of violence, often followed by suicide

A

Amok

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15
Q

What is schizotypal personality disorder

A

Paranoid, odd or magical beliefs, eccentric

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16
Q

What is schizoid personality disorder

A

distant, detached, unemotional, and prefer to be alone

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17
Q

DSM criteria for major depressive episode (including time frame)

A

At least 5 of the following sx for at least 2-weeks:

  • Depressed mood most of the time
  • Anhedonia
  • Change in appetite or weight
  • Worthlessness or guilt
  • Insomnia or hypersomnia
  • Diminished conentration
  • Psychomotor agitation or retardation
  • Fatigue or loss of energy
  • Recurrent thoughts of death or suicide
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18
Q

DSM criteria of manic episode (including time frame)

A

Distinct period of abnormally and persistently elevated, expansive, or irritable mood and abnormally and persistenlty increased goal-directed activity or energy lasting at least 1 week (or any duration if hospitalization necessary) and including at least 3 of the following:

  • Distractibility
  • Inflated self-esteem or grandiosity
  • Increase in goal directed activity or psychomotor agitation
  • Decreased need for sleep
  • Flight of ideas or racing thoughts
  • Talkative or pressured speech
  • Excessive involvement in pleasure activities
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19
Q

DIG FAST

A
Distractibility
Insomnia/Impulsive behavior
Grandiosity
Flight of ideas/racing thoughts
Activity/agitation
Speech pressured
Thoughtlessness
20
Q

Difference between mania and hypomania

A

Mania lasts at least 7 days vs. hypomania at least 4 days

Hypomania does not cause marked impairment in social or occupational functioning

No psychotic features in hypomania

21
Q

DSM Criteria for MDD

A

At least one major depressive episode

No history of manic or hypomanic episodes

22
Q

What type of sleep disturbance is most common in MDD

A

Initial and terminal insomnia (hard to fall asleep and early morning awakenings)

Less likely to have hypersomnia

23
Q

How long do major depressive episodes usually last

A

6-12 months

24
Q

Pharmacotherapy for MDD

A

SSRI, SNRI, TCA, MAOI

25
Q

Main side effects of SSRI

A

HA, GI disturbance, sexual dysfunction, rebound anxiety

26
Q

Side effects of TCAs

A

Cardiac arrhythmias, sedation, weight gain orthostatic hypotension, anticholinergic effects

27
Q

Side effects of MAOIs

A

Hypertensive crisis when used with sympathomimetics or ingestion of tyramine-rich foods, Serotonin syndrome, orthostatic hypotension

28
Q

Tx of MDD with psychotic features

A

Antidepressant + atypical antipsychotics

29
Q

What is mood reactivity

A

Can be an atypical feature of MDD where mood brightens in response to positive events

30
Q

What classifies as melancholic features of MDD

A

Anhedonia, early morning awakenings, depression worse in morning, psychomotor disturbance, excessive guilt, anorexia

31
Q

What classifies as atypical features of MDD

A

Hypersomnia, hyperphagia, reactive mood, leaden paralysis, and hypersensitivity to interpersonal rejection

32
Q

What classifies as mixed features of MDD

A

Manic/hypomanic sx present during the majority of days of MDE: elevated mood, grandiosity, talkativeness/pressured speech, flight of ideas/racing thoughts, increased energy/goal-directed activity, excessive involvement in dangerous activities, and decreased need for sleep

33
Q

What classifies as catatonia within MDD

A

Features include catalepsy (immobility), purposeless motor activity, extreme negativism or mutism, bizarre postures, and echolalia (meaningless repetition of another person’s words)

34
Q

What classifies as psychotic features within MDD

A

Presence of delusions and/or hallucinations

35
Q

What classifies as anxious distress within MDD

A

Feeling keyed up/tense, restless, difficulty concentrating, fears of something bad happening, and feelings of loss of control

36
Q

What classifies as peripartum onset of MDD

A

Onset of MDD sx occurs during pregnancy or 4 weeks following deliver

37
Q

What classifies as seasonal pattern of MDD

A

Temporal relationship between onset of MDD and particular time of the year

Triad for seasonal affective disorder:

(1) Irritability
(2) Carbohydrate craving
(3) Hypersomnia

38
Q

Tx for Seasonal affective disorder

A

Light therapy

39
Q

Effective treatment for catatonia

A

Electroconvulsive therapy (ECT)

40
Q

Diagnostic criteria for Bipolar I Disorder

A

Only requirement is the occurrence of a manic episode

Manic episode may have been preceded by and may be followed by hypomanic or major depressive episodes

41
Q

Components of manic episode

A

During period of mood disturbance and increased energy, three or more of the following sx present to a significant degree:

DIG FAST:

  • Distractibility (attention easily drawn to unimportant stimuli
  • Insomnia or decreased need for sleep
  • Grandiosity or inflated self esteem
  • Flight of ideas or subjective experience that thoughts are racing
  • Agitation (purposeless activity) or increased goal-directed activity
  • Speech pressured
  • Thoughtlessess (e.g. reckless activities)
42
Q

Pharmacotherapy for Bipolar I

A
  • Lithium (mood stabilizer)
  • Anticonvulsants: Carbamazepine and Valproic acid (mood stabilizer)
  • Atypical antipsychotics for acute mania

Antidepressants are usually discouraged due to concern for activating mania or hypomania

43
Q

Pharmacotherapy for Bipolar I

A
  • Lithium (mood stabilizer)
  • Anticonvulsants: Carbamazepine and Valproic acid (mood stabilizer)
  • Atypical antipsychotics for acute mania

Antidepressants are usually discouraged due to concern for activating mania or hypomania

44
Q

Best treatment for a pregnant woman who is having a manic episode

A

ECT

45
Q

Diagnostic criteria of Bipolar II

A

One or more major depressive episode + at least one hypomanic episode

If there has been a full manic episode, even in the past, then the diagnosis is Bipolar I not Bipolar II

46
Q

Tx of Bipolar II

A

Currently same as Bipolar I (Lithium, Carbamazepine, Valproic acid, atypical antipsychotics)