Psych 3 Flashcards

1
Q

Major side effect of 1st gen antipsychotics

A

Extrapyrimidal sx:

  • Dystonia (spasms) of face, neck, tongue
  • Parkinsonism (resting tremor, rigidity, bradykinesia)
  • Akathisia (restlessness)
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2
Q

Difference in side effects between high potency and low potency FGA

A

High potency = more extrapyrimidal side effects

Low potency = more anticholingeric and antiadrenergic side effects

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3
Q

Major side effect of 2nd gen antipsychotics

A

Metabolic syndrome:

Increased BP, increased blood sugar, excess body fat, abnl cholesterol

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4
Q

DSM Criteria of Schizoaffective Disorder

A
  • Meet criteria for either a major depressive or manic episode during which psychotic sx consistent with schizophrenia are also met
  • Delusions or hallucinations for 2 weeks in the absence of mood disorder sx (to differentiate from mood disorder with psychotic features)

Laymens terms: Mood episodes and active symptoms of schizophrenia occurring at the same time + at least 2 week lifetime history of delusions or hallucinations in the absence of prominent mood symptoms
Aka normal schizo sometimes and schizo + mood at other times

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5
Q

DSM criteria and time frame for delusional disorder

A
  • One or more delusions for at least 1 month
  • Does not meet criteria for schizophrenia
  • Functioning in life not significantly impaired and behavior not obviously bizarre
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6
Q

Average age of onset of delusional disorder

A

After age 40

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7
Q

Delusion that another person is in love with the individual

A

Erotomanic type of delusional disorder

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8
Q

Delusions of having great talent

A

Grandoise type of delusional disorder

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9
Q

Physical delusions

A

Somatic type of delusional disorder

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10
Q

Delusions of being persecuted

A

Persecutory type of delusional disorder

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11
Q

Delusions of unfaithfulness

A

Jealous type of delusional disorder

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12
Q

Tx of delusional disorder

A

Difficult to treat

Antipsychotics, supportive therapy

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13
Q

Intense anxiety that penis will recede into body, possibly leading to death

A

Koro

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14
Q

Sudden unprovoked outburts of violence, often followed by suicide

A

Amok

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15
Q

What is schizotypal personality disorder

A

Paranoid, odd or magical beliefs, eccentric

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16
Q

What is schizoid personality disorder

A

distant, detached, unemotional, and prefer to be alone

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17
Q

DSM criteria for major depressive episode (including time frame)

A

At least 5 of the following sx for at least 2-weeks:

  • Depressed mood most of the time
  • Anhedonia
  • Change in appetite or weight
  • Worthlessness or guilt
  • Insomnia or hypersomnia
  • Diminished conentration
  • Psychomotor agitation or retardation
  • Fatigue or loss of energy
  • Recurrent thoughts of death or suicide
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18
Q

DSM criteria of manic episode (including time frame)

A

Distinct period of abnormally and persistently elevated, expansive, or irritable mood and abnormally and persistenlty increased goal-directed activity or energy lasting at least 1 week (or any duration if hospitalization necessary) and including at least 3 of the following:

  • Distractibility
  • Inflated self-esteem or grandiosity
  • Increase in goal directed activity or psychomotor agitation
  • Decreased need for sleep
  • Flight of ideas or racing thoughts
  • Talkative or pressured speech
  • Excessive involvement in pleasure activities
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19
Q

DIG FAST

A
Distractibility
Insomnia/Impulsive behavior
Grandiosity
Flight of ideas/racing thoughts
Activity/agitation
Speech pressured
Thoughtlessness
20
Q

Difference between mania and hypomania

A

Mania lasts at least 7 days vs. hypomania at least 4 days

Hypomania does not cause marked impairment in social or occupational functioning

No psychotic features in hypomania

21
Q

DSM Criteria for MDD

A

At least one major depressive episode

No history of manic or hypomanic episodes

22
Q

What type of sleep disturbance is most common in MDD

A

Initial and terminal insomnia (hard to fall asleep and early morning awakenings)

Less likely to have hypersomnia

23
Q

How long do major depressive episodes usually last

A

6-12 months

24
Q

Pharmacotherapy for MDD

A

SSRI, SNRI, TCA, MAOI

25
Main side effects of SSRI
HA, GI disturbance, sexual dysfunction, rebound anxiety
26
Side effects of TCAs
Cardiac arrhythmias, sedation, weight gain orthostatic hypotension, anticholinergic effects
27
Side effects of MAOIs
Hypertensive crisis when used with sympathomimetics or ingestion of tyramine-rich foods, Serotonin syndrome, orthostatic hypotension
28
Tx of MDD with psychotic features
Antidepressant + atypical antipsychotics
29
What is mood reactivity
Can be an atypical feature of MDD where mood brightens in response to positive events
30
What classifies as melancholic features of MDD
Anhedonia, early morning awakenings, depression worse in morning, psychomotor disturbance, excessive guilt, anorexia
31
What classifies as atypical features of MDD
Hypersomnia, hyperphagia, reactive mood, leaden paralysis, and hypersensitivity to interpersonal rejection
32
What classifies as mixed features of MDD
Manic/hypomanic sx present during the majority of days of MDE: elevated mood, grandiosity, talkativeness/pressured speech, flight of ideas/racing thoughts, increased energy/goal-directed activity, excessive involvement in dangerous activities, and decreased need for sleep
33
What classifies as catatonia within MDD
Features include catalepsy (immobility), purposeless motor activity, extreme negativism or mutism, bizarre postures, and echolalia (meaningless repetition of another person's words)
34
What classifies as psychotic features within MDD
Presence of delusions and/or hallucinations
35
What classifies as anxious distress within MDD
Feeling keyed up/tense, restless, difficulty concentrating, fears of something bad happening, and feelings of loss of control
36
What classifies as peripartum onset of MDD
Onset of MDD sx occurs during pregnancy or 4 weeks following deliver
37
What classifies as seasonal pattern of MDD
Temporal relationship between onset of MDD and particular time of the year Triad for seasonal affective disorder: (1) Irritability (2) Carbohydrate craving (3) Hypersomnia
38
Tx for Seasonal affective disorder
Light therapy
39
Effective treatment for catatonia
Electroconvulsive therapy (ECT)
40
Diagnostic criteria for Bipolar I Disorder
Only requirement is the occurrence of a manic episode Manic episode may have been preceded by and may be followed by hypomanic or major depressive episodes
41
Components of manic episode
During period of mood disturbance and increased energy, three or more of the following sx present to a significant degree: DIG FAST: - Distractibility (attention easily drawn to unimportant stimuli - Insomnia or decreased need for sleep - Grandiosity or inflated self esteem - Flight of ideas or subjective experience that thoughts are racing - Agitation (purposeless activity) or increased goal-directed activity - Speech pressured - Thoughtlessess (e.g. reckless activities)
42
Pharmacotherapy for Bipolar I
- Lithium (mood stabilizer) - Anticonvulsants: Carbamazepine and Valproic acid (mood stabilizer) - Atypical antipsychotics for acute mania Antidepressants are usually discouraged due to concern for activating mania or hypomania
43
Pharmacotherapy for Bipolar I
- Lithium (mood stabilizer) - Anticonvulsants: Carbamazepine and Valproic acid (mood stabilizer) - Atypical antipsychotics for acute mania Antidepressants are usually discouraged due to concern for activating mania or hypomania
44
Best treatment for a pregnant woman who is having a manic episode
ECT
45
Diagnostic criteria of Bipolar II
One or more major depressive episode + at least one hypomanic episode If there has been a full manic episode, even in the past, then the diagnosis is Bipolar I not Bipolar II
46
Tx of Bipolar II
Currently same as Bipolar I (Lithium, Carbamazepine, Valproic acid, atypical antipsychotics)