OBGYN 1 Flashcards

1
Q

What do the GP numbers stand for.

E.g. G3P1234

A
G = total pregnancies
P1 = term pregnancies
P2 = preterm pregnancies
P3 = abortion/miscarriage/molar pregnancies/etc
P4 = living children
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2
Q

What are the structural causes of abnormal uterine bleeding

A

PALM
• P = polyp
o Vascular, glandular, fibromusclar, connective tissue
• A = adenomyosis
o Endometrial cells growing within the myometrium
• L = leiomyoma (fibroid)
o Benign neoplastic proliferation of smooth muscle arising from myometrium
• M = malignancy and hyperplasia

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3
Q

What are the nonstructural causes of abnormal uterine bleeding

A
COEIN
•	C = coagulopathy
•	O = ovulatory dysfunction
•	E = endometrial
•	I = iatrogenic 
•	N = not yet classified
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4
Q

Definition of labor

A

Regular contractions + cervical changes

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5
Q

What are the 2 hormones of normal labor

A

Oxytocin and prostaglandin

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6
Q

Effects of oxytocin

A

• Released by the posterior pituitary and responsible for uterine contractions, let-down reflex in a breastfeeding mother, and bonding behavior

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7
Q

Effects of prostaglandin

A

• Released in tissue throughout the body and responsible for smooth muscle contraction of the uterus and the biophysical changes associated with ripening of the cervix

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8
Q

What is the 1st stage of labor

A

• From the onset of labor (closed cervix) to complete dilation of cervix

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9
Q

What are the 2 phases in the 1st stage of labor

A
  • Latent phase (closed cervix to 6 cm)

- Active phase (6 cm to complete dilation)

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10
Q

What is the 2nd stage of labor

A
  • Pushing and delivery of baby
  • Complete dilation of the cervix
  • Often accompanied by an urge to bear down
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11
Q

What is the 3rd stage of labor

A
•	Placental delivery
•	Signs of separation
- Lengthening of the cord
- Bleeding
- Uterus becomes firm and globular
•	Delivery of placenta with gentle cord traction and counter pressure on uterus above symphysis pubis
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12
Q

What is the fourth stage of labor

A
  • The first hour immediately after delivery of infant
  • Close observation of vital signs
  • Monitor fundus for firmness
  • Monitor perineum for bleeding/ lochia
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13
Q

Describe fetal heart rate decelerations

A

♣ V = variable decelerations . . . C = cord compression
♣ E = early decelerations . . . H = head compression
♣ A = acceleration . . . O = oxygenation
♣ L = late decelerations . . . P = placental insufficiency

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14
Q

Normal blood loss for vaginal birth

A

< 500 cc

>500 = hemorrhage

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15
Q

Normal fetal heart rate baseline

A

110-160

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16
Q

Normal frequency of contractions

A

5 or fewer contractions in 10 minutes, averaged over a 30 minute window (Q2 minutes)

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17
Q

What are 3 broad categories of dystocia

A

Dystocia = difficult labor

♣ Power - are the contractions strong enough?
♣ Passenger – what is the position of the fetus?
♣ Pelvis - what are the pelvic diameters?

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18
Q

Common causes of labor dystocia

A
♣	Abnormal fetal position
♣	Congenital Anomalies
♣	Hypotonic uterine contraction
♣	Excessive Conduction Anesthesia
♣	Cephalopelvic disproportion (CPD) 
♣	Macrosomia (>4500 gm)
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19
Q

What are the 4 components we care about in fetal heart rate

A
  • baseline
  • variability
  • accelerations
  • decelerations
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20
Q

What does FHR variability tell you

A

• It is an indication of central nervous system development and oxygenation.

21
Q

What is normal FHR variability

A

Moderate = 6-25

22
Q

What does absent FHR variability indicate

A

o Can be associated with sleep cycles, medication effects, fetal acidosis

23
Q

What does marked FHR variability indicate

A

> 25 bpm

o Mild hypoxia, fetal activity, medications

24
Q

What does a sinusoidal FHR pattern mean

A

• Shows a very regular pattern
o Fetal anemia, fetal bleeding, fetal isoimmunization, TTTS, cord occlusion, CNS malformations
o Requires immediate delivery

25
Q

What do FHR accelerations indicate

A

• Indicates normal fetal acid-base status. Fetus is well-oxygenated

26
Q

What does FHR early decelerations look like and indicate

A

o Nadir (largest point of trough) simultaneous with peak of contraction.

o Often vagal response from head compression

27
Q

What does FHR late decelerations look like and indicate

A

o Nadir after peak of contraction.
o Placental insufficiency. Excessive uterine contractions, maternal hypotension, maternal hypoxemia, reduced maternal placental exchange as in hypertensive disorders, diabetes, IUGR abruption

28
Q

What doe FHR variable decelerations look like and indicate

A

o Abrupt onset.
o <30 seconds from onset to beginning of nadir lasting > 15 seconds but < 2 minutes, depth >15 bpm
o Cord compression, movement in the premature fetus

29
Q

Describe Non-stress test (NST)

A

♣ Gather all previous data and determine if the FHR is REACTIVE or NON-REACTIVE
♣ A Reactive NST
• An increase of 15 BPM above baseline for 15 second duration (from baseline to baseline) twice in a 20 minute period.
• Only 65% of fetuses at 28 weeks are reactive by this criteria.
• By 34 weeks 95% of fetuses are reactive.

30
Q

Describe components of category I FHR (baseline, variability, decelerations, acceleration)

A
Cat I = good!
o	Baseline rate: 110-160 beats per minute (bpm)
o	Baseline FHR variability: moderate
o	Late or variable decelerations: absent
o	Early decelerations: present or absent
o	Accelerations: present or absent
31
Q

Describe components of Category III FHR (baseline, variability, deceleration, acceleration)

A
Cat III = bad!
o	Absent baseline FHR variability and any of the following:
♣	Recurrent late decelerations
♣	Recurrent variable decelerations
♣	Bradycardia
o	Sinusoidal pattern
32
Q

How does HPV cause cancer? (activation of oncogenes)

A

E6 increases degradation of p53

E7 inactivates the RB gene, which leads to increased synthesis of he intracellular protein p16

33
Q

What are the cardinal movements of labor

A

Descent –> flexion –> internal rotation –> extension –> external rotation –> expulsion

34
Q

When during pregnancy do you give RhoGAM to an Rh neg mom

A

28 weeks

35
Q

What is the range that is considered term pregnancy

A

37-42 weeks

36
Q

Why is magnesium given in pregnant patients

A

Seizure prophylaxis for pre-eclampsia

37
Q

Signs of magnesium toxicity

A

Loss of deep tendon reflexes, HA, vision changes, SOB/chest pain (pulmonary edema), RUQ pain

38
Q

Most accurate clinical indicator of resolution of pre-ecclampsia

A

Diuresis (good urine output)

39
Q

What are the 3 P’s to think about when there is arrest of labor

A
  • Power (contractions)
  • Passenger (
  • Pelvis (pelvis is too small or baby is too large)
40
Q

What is tachysystole

A

Uterine contractions > 5/10 min (> every 2 min)

41
Q

Intervention for tachysystole

A

Decrease or stop oxcytocin, or administer beta-mimetic agent (e.g. Terbutaline) for uterine relaxation

42
Q

Intervention for low BP following epidural or spinal

A

IV fluid bolus, or administer vasopressor agent such as ephedrine

43
Q

Intervention for umbilical prolapse (cord through cervix)

A

Elevate presenting part and emergency C-section

44
Q

Intervention for placental abruption

A

Support BP, stabilize patient, consider C-section if progressive

45
Q

Intervention for uterine rupture

A

Emergency C-section

46
Q

Definition of arrest of active labor

A

• No progress in the active phase of labor (>6 cm) with ruptured membranes for 4 hours without adequate contractions, or 6 hours of inadequate contractions

47
Q

Treatment of repetitive deep variable decelerations

A

Variable decel = cord compression

Tx = amnioinfusion to help alleviate cord compression

48
Q

Tx of repetitive late decelerations after epidural

A

Epidural can lead to hypotension in mom –> placental insufficiency

Tx = IV fluids, then vasopressor (e.g. Ephedrine - causes vasoconstriction of the peripheral vasculature but spares the uterine arteries)

49
Q

What are the 4 signs of placental separation

A

(1) Gush of blood
(2) Lengthening of cord
(3) Firm and globular shape of uterus
(4) Uterus rises up to anterior abd wall