Supplements, Genes (25/26)! Flashcards

1
Q

Products considered supplements

A

-vitamins and minerals
-probiotics and prebiotics
-herbal remedies
-homeopathic medicines
-traditional medicines
-amino acids, fatty acids

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2
Q

What regulations are in effect by Health Canada or FDA

A

-no vigorous testing
-have natural product number (NPN- does not require much effort)

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3
Q

What documents have to be submitted by companies to receive an NPN?

A

Prove:
-safety
-effective
-high quality

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4
Q

United States Pharmacopeia (USP) Dietary Supplement Verification Program

A

-voluntary program open to manufacturers
-standards made according to FDA current Good Manufacturing Practices
-sanitary and well controlled procedures

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5
Q

What does USP regulation include?

A

-ingredients lists
-declared potency and actual amounts
-check for harmful contaminants
-break down time

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6
Q

Potency- Vitamin E, better natural or as supplement?

A

natural 2x as potent

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7
Q

Potency- Vitamin C, better natural or as supplement?

A

equal potency

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8
Q

When do you take a multivitamin?

A

With a meal

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9
Q

When should you take your iron supplement

A

-with meal or glass of juice
-avoid w/ tea or coffee
-if anemic, not at same time as Ca

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10
Q

When should you take your calcium supplement

A

-with meal
-divide large doses
-calcium and vitamin D is a good idea in winter (if not multivitamin)

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11
Q

Main organs that are damaged if whey protein usage is abused

A

-liver, kidney, microbiota, skin

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12
Q

What is whey protein good for?

A

-improving sport performance
-immunomodulation
-antibacterial, antiviral, and antifungal properties

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13
Q

Creatine

A

-increases bioavailability of phosphocreatine in muscles
-faster synthesis of ATP
-good for brief, high intensity exercise

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14
Q

How does that body naturally synthesize phosphocreatine?

A

from amino acids

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15
Q

What population may benefit in particular from a creatine supplement?

A

vegetarians

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16
Q

Omega 3 supplements help w/?

A

-heart health
-autoimmune diseases
-depression
-brain development in infancy

17
Q

Dangers of high doses of omega 3 (fatty acids)

A

-high blood sugar
-bleeding
-low blood pressure
-diarrhea
-acid reflux

18
Q

Considerations about herbal substances

A

-considered natural (healthier/safer)
-lacking well-controlled studies
-many herbs have damaging effects
-many inhibit or strengthen effects of prescription medications

19
Q

Probiotics

A

-live microbes
-health benefits when taken in sufficient amounts

20
Q

Prebiotics

A

-food for microbes
-confer health benefits

21
Q

Side effects of probiotics

A

-unpleasant digestive system symptoms
-allergic reactions
-infection and sepsis
-may interact poorly w/ some medicines

22
Q

Side effects of prebiotics

A

-unpleasant digestive system symptoms
-gastroesophageal reflux (large doses)
-irritable bowel syndrome worsened

23
Q

Common disease resulting from single gene defects

A

-PKU (phenylketonuria)
-cystic fibrosis
-sick cell anemia
-hemochromatosis

24
Q

Common diseases resulting from polygenic (multiple) defects

A

-heart disease
-cancer
-hypertension
-obesity

25
Q

celiac disease

A

-autoimmune condition that damages small intestine
-react to gluten (wheat, barley, rye)
-DQ2 or DQ8 version of HLA gene

26
Q

Classic symptoms of celiac disease

A

-headache
-fatigue
-abdominal pain and bloating (after consumption)
-weight loss
-diarrhea
-constipation
-foul smelling stools

27
Q

Non-celiac gluten sensitivity

A

-no biomarkers for diagnosis
-no autoantibodies (TTG< EMA< DGP)
-no villous atrophy

28
Q

Nutrigenetics

A

-study of how genes and diet interact to increase/decrease someone’s risk of disease
-gene x environment