stress and immune responses Flashcards

1
Q

what is stress`

A

exposure to harm or threat

causes physiological changes hr/br

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2
Q

where does a stress response begin

A

nucleus of the hypothalamus

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3
Q

where is ATCH released from

A

pituitary gland

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4
Q

what does acth cause release of

A

glucocorticods from the adrenal cortex

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5
Q

which system to stressors activate

A

sympathetic nervous system

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6
Q

what is released from the sympathetic nervous system caused by stressors

A

adrenaline and nor adrenaline

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7
Q

where is adrenaline and nor adrenaline released from

A

adrenal medulla

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8
Q

what effect do stressors have on cytokines

A

stressors increase the production of cytokines

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9
Q

define psychoneuroimmunology

A

effect of the mind on health and drug resistance

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10
Q

what is the link betwee stress and gastric ulcers

A

higher levels of stress = more susceptible to gastric ulcers

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11
Q

what bacteria causes a gastric ulcer

A

H-pylori

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12
Q

what is a gastric ulcer

A

lesion on stomach lining

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13
Q

state the 2 lines of defense in the immune system

A
  1. innate immune system

2. adaptive immune system

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14
Q

what are cytokines

A

small proteins produced by immune cells

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15
Q

what is the function of cytokines

A

promote healing of damaged tissue

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16
Q

state the processes that occur in the innate immune system

A

pathogens cause swelling

cytokines are released whcih attract phagocytes and leukocytes

17
Q

what is the function of the adaptive immune system

A

destroys cells that have already been attacked by phagocytes

18
Q

what is a lymphocyte

A

specialised white blood cell in the lymphatic system

19
Q

what immunity does a T cell produce

A

cell mediated immunity

20
Q

describe the process of a t cell

A

bind to macrophage

t cell would multiply, created more t cells to destroy pathogen

21
Q

what immunity does a B cell produce

A

antibody mediated immunity

22
Q

describe the immunity process of a B cell

A

B cell bind with antigen
B cell replicate and release the specific antibody to the antigen
antibody kill micro-organism

23
Q

what is the advantage of the memory component of the adaptive immune system

A

allow vaccinations to have their preventative effect

provide immunisation

24
Q

define acute stress

A

good to fight infection

25
Q

what do short term cytokines do

A

combat infection

26
Q

define chronic stress

A

immune system becomes less effective

27
Q

what do long term cytokines do

A

cause problems or long term health consequences

28
Q

what are T and B cells receptors for

A

glucocorticods

29
Q

what are lymphocytes receptors for

A

glucocorticods, adrenaline and nor adrenaline

30
Q

which brain region has lots of glucocorticods receptors

A

hippocampus

31
Q

what are the risks of a small hippocampus

A

increased risk of stress

increased risk of ptsd

32
Q

what is the effect of stress mediated by

A

glucocorticoid levels

33
Q

if a pup was raised by an anxious mother, what effect would this have on adulthood for the pup

A

anxious adult

34
Q

what effect did meditation have on stress response

A

increased production of antibody in meditation group compared to control group
led to increased immune response to vaccination

35
Q

state two types of stress

A

acute and chronic stress

36
Q

what is the function of the innate immune system

A

react quickly to pathogens

activated by toll like receptors

37
Q

define phagocyte

A

ingestion of bacteria or other material